Updating the Artech House bestseller, "Fundamentals and Applications of Microfluidics", this newly revised second edition provides electrical and mechanical engineers with complete and current coverage of microfluidics - an emerging field involving fluid flow and devices in microscale and nanoscale. The second edition offers a greatly expanded treatment of nanotechnology, electrokinetics and flow theory. The book shows engineers how to take advantage of the performance benefits of microfluidics and serves as an instant reference for state-of-the-art microfluidics technology and applications. The wide range of applications discussed includes fluid control devices, gas and fluid measurement devices, medical testing equipment, and implantable drug pumps. Professionals learn how to choose the best fabrication and enabling technology for a specific microfluidic application.

Part I. Micro and Nanoscale Biosensors and Materials: Biosensors and Biochips.- Cantilever Assays: A Universal Platform for Multi-plexed Label-Free Bioassays.- An On-chip Artificial Pore For Molecular Sensing.- Cell Based Chemical Sensing Technologies.- Fabrication issues of Biomedical Micro Devices.- Intelligent Polymeric Networks in Biomolecular Sensing.- Part II Processing and Integrated Systems: A Multi-Functional Micro Total Analysis System ( TAS) Platform for Transport and Sensing of Biological Fluids using Microchannel Parallel Electrodes.- Dielectrophoretic Traps for Cell Manipulation.- BioMEMS for Cellular Manipulation and Analysis.- Implantable Wireless Microsystems.- Microfluidic Tectonics: An integrated organic autonomous platform.- AC Electrokinetic Stirring and Focusing of Nanoparticles.- Part III. Micro-fluidics and Characterization: Particle Dynamics in a Dielectrophoretic Microdevice.- Microfluidics Simulations I.- Modeling Electroosmotic Flow in Nanochannels.- Nano-Particle Image Velocimetry: A Near-Wall Velocimetry Technique with Submicron Spatial Resolution.- Optical MEMS-Based Sensor Development with Applications to Microfluidics.- Vascular Cell Responses to Fluid Shear Stress.

This immensely practical guide to PIV provides a condensed, yet exhaustive guide to most of the information needed for experiments employing the technique. This second edition has updated chapters on the principles and extra information on microscopic, high-speed and three component measurements as well as a description of advanced evaluation techniques. What's more, the huge increase in the range of possible applications has been taken into account as the chapter describing these applications of the PIV technique has been expanded.

Less than twenty years ago photolithography and medicine were total strangers to one another. They had not yet met, and not even looking each other up in the classi?eds. And then, nucleic acid chips, micro?uidics and microarrays entered the scene, and rapidly these strangers became indispensable partners in biomedicine. Asrecentlyastenyearsagothenotionofapplyingnanotechnologytothe?ghtagainstd- ease was dominantly the province of the ?ction writers. Thoughts of nanoparticle-vehicled deliveryoftherapeuticalstodiseasedsiteswereanexerciseinscienti?csolitude,andgrounds for questioning one's ability to think "like an established scientist". And today we have nanoparticulate paclitaxel as the prime option against metastatic breast cancer, proteomic pro?lingdiagnostictoolsbasedontargetsurfacenanotexturing,nanoparticlecontrastagents for all radiological modalities, nanotechnologies embedded in high-distribution laboratory equipment, and no less than 152 novel nanomedical entities in the regulatory pipeline in the US alone. Thisisatransformingimpact,byanymeasure,withclearevidenceoffurtheracceleration, supported by very vigorous investments by the public and private sectors throughout the world. Even joining the dots in a most conservative, linear fashion, it is easy to envision scenarios of personalized medicine such as the following: patient-speci?c prevention supplanting gross, faceless intervention strategies; early detection protocols identifying signs of developing disease at the time when the disease is most easily subdued; personally tailored intervention strategies that are so routinely and inexpensively realized, that access to them can be secured by everyone; technologies allowing for long lives in the company of disease, as good neighbors, without impairment of the quality of life itself.

This immensely practical guide to PIV provides a condensed, yet exhaustive guide to most of the information needed for experiments employing the technique. This second edition has updated chapters on the principles and extra information on microscopic, high-speed and three component measurements as well as a description of advanced evaluation techniques. What's more, the huge increase in the range of possible applications has been taken into account as the chapter describing these applications of the PIV technique has been expanded.