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Mathematical and computational biology is playing an increasingly
important role in the biological sciences. This science brings
forward unique challenges, many of which are, at the moment, beyond
the theoretical techniques available. Developmental biology, due to
its complexity, has lagged somewhat behind its sister disciplines
(such as molecular biology and population biology) in making use of
quantitative modeling to further biological understanding. This
volume comprises work that is among the best developmental modeling
available and we feel it will do much to remedy this
situation.
This book is aimed at all those with an interest in the
interdisciplinary field of computer and mathematical modeling of
multi-cellular and developmental systems. It is also a goal of the
Editors to attract more developmental biologists to consider
integrating modeling components into their research. Most
importantly, this book is intended to serve as a portal into this
research area for younger scientists - especially graduate students
and post-docs, from both biological and quantitative backgrounds.
* Articles written by leading exponents in the field
* Provides techniques to address multiscale modelling
* Coverage includes a wide spectrum of modeling approaches
* Includes descriptions of the most recent advances in the field
During development cells and tissues undergo changes in pattern and
form that employ a wider range of physical mechanisms than at any
other time in an organism's life. This book shows how physics can
be used to analyze these biological phenomena. Written to be
accessible to both biologists and physicists, major stages and
components of the biological development process are introduced and
then analyzed from the viewpoint of physics. The presentation of
physical models requires no mathematics beyond basic calculus.
Physical concepts introduced include diffusion, viscosity and
elasticity, adhesion, dynamical systems, electrical potential,
percolation, fractals, reaction-diffusion systems, and cellular
automata. With full-color figures throughout, this comprehensive
textbook teaches biophysics by application to developmental biology
and is suitable for graduate and upper-undergraduate courses in
physics and biology.
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