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This study was carried out on 90 one-day-old broiler chicks to know
clinico-hematological alterations, DNA damage caused by
cypermethrin (CY), and attenuation of toxic effects by vitamin E
(Vit E) and selenium (Se). Birds were randomly divided into five
equal groups.Birds were monitored twice daily for clinical signs.
They were weighed and blood samples were collected for
hematological studies. CY-treated birds showed more prominent signs
of toxicity compared to CY+Vit E, CY+Se and CY+Vit E+Se birds. Body
weight in groups 1-3 was significantly (P>0.05) smaller at days
20 and 30 when compared with the control group. Significantly
(P>0.001) higher numbers of micronuclei appeared in chicks
treated with CY compared to CY+Vit E- and CY+Se-treated birds.
Significantly decreased total erythrocyte counts (TEC), hemoglobin
(Hb) concentration and packed cell volume (PCV) in all treated
groups were recorded.It can be concluded that CY induces toxic
effects in broilers chicks; however, these toxic effects can be
ameliorated by Vit E or Se. Combination of Vit E and Se was more
effective to ameliorate toxic effects of cypermethrin.
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