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This comprehensive, up-to-date reference work compiles the
scientific research on the relationship between various forms of
cancer and reactive oxygen species (ROS). It is well known that ROS
play a key role in the various steps leading to malignancy, this
includes increase in DNA mutation rates. The book brings together
exciting reviews, written by leading experts all over the world.
The book is divided into four broad sections. Each section
describes the role of oxidative stress and underlying mechanisms
and pathways, at various stages of cancer, including its role in
carcinogenesis, cancer progression and metastasis. Further, the
book describes how the reactive oxygen species (ROS) modulate gene
expression and signal transduction pathways in cancer. The book
discusses the ways to interfere with the cancer progression, and
design of anti-cancer drugs. The book provides an integrated
approach for better understanding of the development phases of
oxidative stress-induced cancers, and mainly the current
perspectives about mechanistic aspects of cancer initiation,
progression and metastasis. It is a highly resourceful book and
would be extremely important to clinicians, students and
researchers in the field of cancer genetics, therapeutics and
oncology.
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