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Showcases the important role of organometallic chemistry in
industrial applications and includes practical examples and case
studies This comprehensive book takes a practical approach to how
organometallic chemistry is being used in industrial applications.
It uniquely offers numerous, real-world examples and case studies
that aid working R&D researchers as well as Ph.D. and postdoc
students preparing to ace interviews in order to enter the
workforce. Edited by two world-leading and established industrial
chemists, the book covers flow chemistry (catalytic and
non-catalytic organometallic chemistry), various cross-coupling
reactions (C-C, C-N, and C-B) in classical batch chemistry,
conjugate addition reactions, metathesis, and C-H arylation and
achiral hydrogenation reactions. Beginning with an overview of the
many industrial milestones within the field over the years,
Organometallic Chemistry in Industry: A Practical Approach provides
chapters covering: the design, development, and execution of a
continuous flow enabled API manufacturing route; continuous
manufacturing as an enabling technology for low temperature
organometallic chemistry; the development of a nickel-catalyzed
enantioselective Mizoroki-Heck coupling; and the development of
iron-catalyzed Kumada cross-coupling for the large scale production
of Aliskiren intermediates. The book also examines aspects of
homogeneous hydrogenation from industrial research; the latest
industrial uses of olefin metathesis; and more. -Includes rare
industrial case studies difficult to find in current literature
-Helps readers successfully carry out their own reactions -Covers
topics like flow chemistry, cross-coupling reactions, and
dehydrative decarbonylation -Features a foreword by Nobel Laureate
R. H. Grubbs -A perfect resource for every R&D researcher in
industry -Useful for PhD students and postdocs: excellent
preparation for a job interview Organometallic Chemistry in
Industry: A Practical Approach is an excellent resource for all
chemists, including those working in the pharmaceutical industry
and organometallics.
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