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Knowledge is of two kinds. We know a subject ourselves, or we know
where we can find information on it Samuel Johnson, 18 April, 1775*
Sterols are among the most studied groups of natural products with
interest commencing in the 19th century and running to the present.
Investigations have embraced the refinement of separation
procedures, the development of new analytical techniques and
instrumentation for structure elucidation, the unravelling of
biosynthetic mechanisms, the determination of the physiological
functions of sterols, and the role they play in health and disease.
In the past 20-30 years interest in the medical implications of
sterol biochemistry, studies on the sterols of plants, algae and
fungi, and the identification of the many unusual sterols from
marine organisms have proceeded in parallel and somewhat
independently. Although the motiva tion and goals for the various
lines of investigation have differed widely the researchers working
in each of these areas have contributed a wealth of knowledge to
the literature relating to the analysis of sterols and many diverse
new sterols have been discovered. We conceived this book as a
modest attempt to bring together some of this literature in the
hope that it may be helpful to newcomers to sterol research. We had
originally intended to produce a 'handbook' outlining in detail the
protocols to be followed for sterol extraction, chromatography, NMR
analysis, etc. in order to identify the components of a sterol
mixture."
Knowledge is of two kinds. We know a subject ourselves, or we know
where we can find information on it Samuel Johnson, 18 April, 1775*
Sterols are among the most studied groups of natural products with
interest commencing in the 19th century and running to the present.
Investigations have embraced the refinement of separation
procedures, the development of new analytical techniques and
instrumentation for structure elucidation, the unravelling of
biosynthetic mechanisms, the determination of the physiological
functions of sterols, and the role they play in health and disease.
In the past 20-30 years interest in the medical implications of
sterol biochemistry, studies on the sterols of plants, algae and
fungi, and the identification of the many unusual sterols from
marine organisms have proceeded in parallel and somewhat
independently. Although the motiva tion and goals for the various
lines of investigation have differed widely the researchers working
in each of these areas have contributed a wealth of knowledge to
the literature relating to the analysis of sterols and many diverse
new sterols have been discovered. We conceived this book as a
modest attempt to bring together some of this literature in the
hope that it may be helpful to newcomers to sterol research. We had
originally intended to produce a 'handbook' outlining in detail the
protocols to be followed for sterol extraction, chromatography, NMR
analysis, etc. in order to identify the components of a sterol
mixture."
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