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This book introduces readers to the principles of laser interaction
with biological cells and tissues with varying degrees of
organization. In addition to considering the problems of biomedical
cell diagnostics, and modeling the scattering of laser irradiation
of blood cells for biological structures (dermis, epidermis,
vascular plexus), it presents an analytic theory based on solving
the wave equation for the electromagnetic field. It discusses a
range of mathematical modeling topics, including optical
characterization of biological tissue with large-scale and
small-scale inhomogeneities in the layers; heating blood vessels
using laser irradiation on the outer surface of the skin; and
thermo-chemical denaturation of biological structures based on the
example of human skin. In this second edition, a new electrodynamic
model of the interaction of laser radiation with blood cells is
presented for the structure of cells and the in vitro prediction of
optical properties. The approach developed makes it possible to
determine changes in cell size as well as modifications in their
internal structures, such as transformation and polymorphism
nucleus scattering, which is of interest for cytological studies.
The new model is subsequently used to calculate the size
distribution function of irregular-shape particles with a variety
of forms and structures, which allows a cytological analysis of the
observed deviations from normal cells.
This book is devoted to the physical and mathematical modeling of
the formation of complexes of protein molecules. The models
developed show remarkable sensitivity to the amino acid sequences
of proteins, which facilitates experimental studies and allows one
to reduce the associated costs by reducing the number of
measurements required according to the developed criteria. These
models make it possible to reach a conclusion about the
interactions between different amino acid chains and to identify
more stable sites on proteins. The models also take the
phosphorylation of amino acid residues into account. At the end of
the book, the authors present possible directions of application of
their physical and mathematical models in clinical medicine.
This book is devoted to the physical and mathematical modeling of
the formation of complexes of protein molecules. The models
developed show remarkable sensitivity to the amino acid sequences
of proteins, which facilitates experimental studies and allows one
to reduce the associated costs by reducing the number of
measurements required according to the developed criteria. These
models make it possible to reach a conclusion about the
interactions between different amino acid chains and to identify
more stable sites on proteins. The models also take the
phosphorylation of amino acid residues into account. At the end of
the book, the authors present possible directions of application of
their physical and mathematical models in clinical medicine.
This book introduces readers to the principles of laser interaction
with biological cells and tissues with varying degrees of
organization. In addition to considering the problems of biomedical
cell diagnostics, and modeling the scattering of laser irradiation
of blood cells for biological structures (dermis, epidermis,
vascular plexus), it presents an analytic theory based on solving
the wave equation for the electromagnetic field. It discusses a
range of mathematical modeling topics, including optical
characterization of biological tissue with large-scale and
small-scale inhomogeneities in the layers; heating blood vessels
using laser irradiation on the outer surface of the skin; and
thermo-chemical denaturation of biological structures based on the
example of human skin. In this second edition, a new electrodynamic
model of the interaction of laser radiation with blood cells is
presented for the structure of cells and the in vitro prediction of
optical properties. The approach developed makes it possible to
determine changes in cell size as well as modifications in their
internal structures, such as transformation and polymorphism
nucleus scattering, which is of interest for cytological studies.
The new model is subsequently used to calculate the size
distribution function of irregular-shape particles with a variety
of forms and structures, which allows a cytological analysis of the
observed deviations from normal cells.
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