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This book presents a comprehensive review of the morphology and
function of chromosomes in elderly people. The wide range of topics
includes cyclical chromosome properties, mutations, repair,
progressive chromosome heterochromatinization with increasing age,
roles of nucleolar organiser regions, sister chromatid exchanges,
homologue relationships, heterochromatin regions and other
chromosomal features in very old age. This ground-breaking book
focuses on heterochromatinisation as a key determinant of the
genetic apparatus function during senescence and an area to seek
life-prolonging interventions. The book illustrates and updates
progress in the field of cytogenetics of ageing. The book contains
16 tables and 25 figures.
This book presents a comprehensive review of the morphology and
function of chromosomes in elderly people. The wide range of topics
includes cyclical chromosome properties, mutations, repair,
progressive chromosome heterochromatinisation with increasing age,
roles of nucleolar organiser regions, sister chromatid exchanges,
homologue relationships, heterochromatin regions and other
chromosomal features in very old age. This ground-breaking book
focuses on heterochromatinisation as a key determinant of the
genetic apparatus function during senescence and an area to seek
life-prolonging interventions. The book illustrates and updates
progress in the field of cytogenetics of ageing.
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