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In this second edition, the authors present a thorough, advanced
review of the interactions between motoneurones and muscles in
vertebrates. The book discusses the significance of nerve-muscle
interactions for the normal development and maintenance of the
vertebrate neuromuscular system and reviews the consequences of
their disruption. The plasticity of nerve-muscle interactions and
the potential for repair is analyzed, as is the importance of
neuromuscular activity in development. The subject is approached
from a broad viewpoint and the authors integrate results from many
disciplines to illustrate the significance of neuromuscular
interaction for normal locomotor activity. This approach makes the
book useful for clinical researchers of neuromuscular disease.
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