Much of our knowledge of stem cells has been inferred from studies of remarkable few species. The ability to manipulate stem cells in model organisms such as the mouse and a few other vertebrate species has driven our understanding of basic biology of stem cells. The power and efficiency of studying model organisms, however, comes at a cost since a few species, obviously, do not reflect nature?'s true diversity. Unfortunately, although all multicellular organisms seem to rely on stem cells, and although this seems to be a question of key importance for understanding the evolution of animal life, little is known about stem cells in early-branching taxa. The book Stem Cells: From Hydra to Man illustrates that here is more than human and mouse stem cells to learn from. Reflecting an enormous growth in the knowledge of stem cells in various organisms, the book presents the conceptual language and the nature of questions, as well as a summary of the advances in our understanding of stem cells from a comparative point of view that has resulted from the development of new technology and the development of novel model organisms over the past few decades. As such this book is largely a horizon analysis of a frontier rather than a retrospective. It presents an integrative approach to animal stem cells and covers the major contributions, tools and trends in a newly emerging field: comparative stem cell biology.

This book examines how the growing knowledge of the huge range of protist-, animal-, and plant-bacterial interactions, whether in shared ecosystems or intimate symbioses, is fundamentally altering our understanding of biology. The establishment and maintenance of these interactions and their contributions to the health and survival of all partners relies on continuous cell-to-cell communication between them. This dialogue may be concerned with all aspects of the biology of both partners. The book includes chapters devoted to exploring, explaining, and exposing these dialogues across a broad spectrum of plant and animal eukaryotes to a broad field of biologists. Key Features Explores the nature of the interactions between eukaryotic hosts and their microbial symbionts Examines the links between prostist, animal, and plant evolution and microbial communities Reviews specific taxa and the microbial diversity associated with these taxa Illustrates the role microbes play in the physiology and etiology of several model species Includes chapters by an international team of leading scholars

This book examines how the growing knowledge of the huge range of protist-, animal-, and plant-bacterial interactions, whether in shared ecosystems or intimate symbioses, is fundamentally altering our understanding of biology. The establishment and maintenance of these interactions and their contributions to the health and survival of all partners relies on continuous cell-to-cell communication between them. This dialogue may be concerned with all aspects of the biology of both partners. The book includes chapters devoted to exploring, explaining, and exposing these dialogues across a broad spectrum of plant and animal eukaryotes to a broad field of biologists. Key Features Explores the nature of the interactions between eukaryotic hosts and their microbial symbionts Examines the links between prostist, animal, and plant evolution and microbial communities Reviews specific taxa and the microbial diversity associated with these taxa Illustrates the role microbes play in the physiology and etiology of several model species Includes chapters by an international team of leading scholars

Much of our knowledge of stem cells has been inferred from studies of remarkable few species. The ability to manipulate stem cells in "model" organisms such as the mouse and a few other vertebrate species has driven our understanding of basic biology of stem cells. The power and efficiency of studying model organisms, however, comes at a cost since a few species, obviously, do not reflect natures true diversity. Unfortunately, although all multicellular organisms seem to rely on stem cells, and although this seems to be a question of key importance for understanding the evolution of animal life, little is known about stem cells in early-branching taxa.

The book "Stem Cells: From Hydra to Man" illustrates that here is more than human and mouse stem cells to learn from. Reflecting an enormous growth in the knowledge of stem cells in various organisms, the book presents the conceptual language and the nature of questions, as well as a summary of the advances in our understanding of stem cells from a comparative point of view that has resulted from the development of new technology and the development of novel model organisms over the past few decades. As such this book is largely a horizon analysis of a frontier rather than a retrospective. It presents an integrative approach to animal stem cells and covers the major contributions, tools and trends in a newly emerging field: comparative stem cell biology.

Wir sind viele und haben mindestens ebenso viele Bakterienzellen wie eigene Zellen in unserem Koerper. Was weiss man uber die Funktion, die die Mikroben fur Mensch und Tier hat? Thomas Bosch, Evolutions- und Entwicklungsbiologe und Experte auf dem Gebiet der Mikrobiomforschung, blickt bei dieser Frage auf die Fulle an Forschungsergebnissen und auch auf seine eigene Forschung zuruck. Wir werden dazu angeregt, beim Nachdenken uber die ansteigende Zahl an "Lifestyle" Erkrankungen in einem ganzheitlichen Ansatz die Bedeutung des Mikrobioms zu berucksichtigen. Wir sind viele und wir waren schon immer viele, auch in der Evolutionsgeschichte. Ohne Mikroben koennen wir uns nicht normal entwickeln und sind krank. Wie wir leben und uns ernahren hat starken Einfluss auf die Mikroorganismen. Hinter dieser Erkenntnis steckt auch die Perspektive, durch Eingriffe in das Mikrobiom unsere Gesundheit zu erhalten. Die Komplexitat der Mikrobiomforschung kann als kompakte Erzahlung schwer zu verdauen sein. Dieses Buch kann es.