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This SpringerBrief provides an overview of ultrasonic
emulsification and an update on recent advances in developing
stable emulsions for the creation of novel drugs and functional
foods, with a focus on bioactive delivery in these products.
Emulsification is the process of combining two or more immiscible
liquids to form a semi-stable mixture. These two liquids generally
consist of an organic (oil) phase and an aqueous (water) phase that
is stabilized by the addition of an emulsifier. Most common
emulsions are of the oil-in-water (O/W) type, but can also be of
water-in-oil (W/O) or even multiple emulsion types (i.e. double
emulsions) in the form of water-in-oil-in-water (W/O/W) or
oil-in-water-in-oil (O/W/O) phases. The formation of an emulsion
requires input of energy to distribute the disperse phase in the
continuous phase in small-sized droplets that are able to resist
instability. There is great interest in the use of ultrasound to
produce emulsions, as it is able to do so relatively efficiently
and effectively compared to existing techniques such as rotor
stator, high-pressure homogenization and microfluidization. The
interaction of ultrasound with the hydrocolloids and biopolymers
that are often used to stabilize emulsions can offer advantages
such as improved stability or greater control of formed droplet
size distributions.
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