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This book covers the latest advances, applications, and challenges
in orthopedic biomaterials. Topics covered include materials for
orthopedic applications, including nanomaterials, biomimetic
materials, calcium phosphates, polymers, biodegradable metals, bone
grafts/implants, and biomaterial-mediated drug delivery. Absorbable
orthopedic biomaterials and challenges related to orthopedic
biomaterials are covered in detail. This is an ideal book for
graduate and undergraduate students, researchers, and professionals
working with orthopedic biomaterials and tissue engineering. This
book also: Describes biodegradable metals for orthopedic
applications, such as Zn-based medical implants Thoroughly covers
various materials for orthopedic applications, including absorbable
orthopedic biomaterials with a focus on polymers Details the
state-of-the-art research on orthopedic nanomaterials and
nanotechnology
This book covers the latest research in biofilm, infection, and
antimicrobial strategies in reducing and treating musculoskeletal,
skin, transfusion, implant-related infections, etc. Topics covered
include biofilms, small colony variants, antimicrobial biomaterials
(antibiotics, antimicrobial peptides, hydrogels, bioinspired
interfaces, immunotherapeutic approaches, and more), antimicrobial
coatings, engineering and 3D printing, antimicrobial delivery
vehicles, and perspectives on clinical impacts. Antibiotic
resistance, which shifts the race toward bacteria, and strategies
to reduce antibiotic resistance, are also briefly touched on.
Combined with its companion volume, Racing for the Surface:
Pathogenesis of Implant Infection and Advanced Antimicrobial
Strategies, this book bridges the gaps between infection and tissue
engineering, and is an ideal book for academic researchers,
clinicians, industrial engineers and scientists, governmental
representatives in national laboratories, and advanced
undergraduate students and post-doctoral fellows who are interested
in infection, microbiology, and biomaterials and devices.
This book covers the key basics of tissue engineering as well as
the latest advances in the integration of both antimicrobial and
osteoinductive properties. Topics covered include osteoconductive
and osteoinductive biomaterials (calcium phosphate, bone
morphogenetic protein, peptides, antibodies, bioactive glasses,
nanomaterials, etc.) and scaffolds. Research integrating both
antimicrobial/biofilm-inhibiting and osteoinductive/osteoconductive
properties and their co-delivery is detailed and their roles in
clinical success are discussed. Combined with its companion volume,
Racing for the Surface: Antimicrobial and Interface Tissue
Engineering, this book bridges the gap between infection and tissue
engineering, and is an ideal book for academic researchers,
clinicians, industrial engineers and scientists, governmental
representatives in national laboratories, and advanced
undergraduate students and post-doctoral fellows who are interested
in tissue engineering and regeneration, infection, and biomaterials
and devices.
This book covers the latest progress in the biology and
manufacturing of orthopedic biomaterials, as well as key industry
perspectives. Topics covered include the development of
biomaterial-based medical products for orthopedic applications,
anti-infection technologies for orthopedic implants, additive
manufacturing of orthopedic implants, and more. This is an ideal
book for graduate students, researchers and professionals working
with orthopedic biomaterials and tissue engineering. This book
also: Provides an industry perspective on technologies to prevent
orthopedic implant related infection Thoroughly covers how to
modulate innate inflammatory reactions in the application of
orthopedic biomaterials Details the state-of-the-art research on 3D
printed porous bone constructs
This book covers the latest progress in the biology and
manufacturing of orthopedic biomaterials, as well as key industry
perspectives. Topics covered include the development of
biomaterial-based medical products for orthopedic applications,
anti-infection technologies for orthopedic implants, additive
manufacturing of orthopedic implants, and more. This is an ideal
book for graduate students, researchers and professionals working
with orthopedic biomaterials and tissue engineering. This book
also: Provides an industry perspective on technologies to prevent
orthopedic implant related infection Thoroughly covers how to
modulate innate inflammatory reactions in the application of
orthopedic biomaterials Details the state-of-the-art research on 3D
printed porous bone constructs
The enormous advances in the immunologic aspects of biotherapeutics
and nanomedicines in the past two decades has necessitated an
authoritative and comprehensive reference source that can be relied
upon by immunologists, biomedical researchers, clinicians,
pharmaceutical companies, regulators, venture capitalists, and
policy makers alike. This text provides a thorough understanding of
immunology, therapeutic potential, clinical applications, adverse
reactions, and approaches to overcoming immunotoxicity of
biotherapeutics and nanomedicines. It also tackles critical, yet
often overlooked topics such as immune aspects of nano-bio
interactions, current FDA regulatory guidances, complement
activation-related pseudoallergy (CARPA), advances in nanovaccines,
and immunogenicity testing of protein therapeutics.
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