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This volume provides a comprehensive overview of recent
developments in magnetic particle imaging (MPI), a novel imaging
modality. Using various static and oscillating magnetic fields, and
tracer materials made from iron oxide nanoparticles, MPI can
perform background-free measurements of the particles' local
concentration. The method exploits the nonlinear remagnetization
behavior of the particles and has the potential to surpass current
methods for the detection of iron oxide in terms of sensitivity and
spatiotemporal resolution. Starting from an introduction to the
technology, the topics addressed include setting up an imaging
device, assessment of image quality, development of new MPI tracer
materials, and the first preclinical results. This is the first
book to be published on magnetic particle imaging, and it will be
an invaluable source of information for everyone with an interest
in this exciting new modality.
Tobias Knopp erlautert die Rekonstruktion von MPI-Daten und
entwickelt auf Grundlage eines Modells der MPI-Signalkette eine
effiziente Methode zur Bestimmung der Systemmatrix. Fur die
Rekonstruktion der ortlichen Partikelverteilung nutzt er einen
gewichteten, regularisierten Kleinste-Quadrate-Ansatz. Im zweiten
Teil der Arbeit stellt der Autor verschiedene neuartige
Spulentopologien vor."
In these proceedings, an overview on recent results of a novel
imaging modality based on magnetic nanoparticles is given. This
imaging concept, called magnetic particle imaging (MPI), falls into
the category of functional imaging and, hence, the magnetic
nanoparticles may serve as tracers of metabolic processes. Today,
there are interesting challenges within the practical set-up of a
scanning device and also in the design of new MPI nanoparticles.
During this workshop at the University of Lubeck in 2010,
scientists from chemical engineering, biology, electrical
engineering, physics, computer sciences and medicine discussed the
promises and challenges of MPI.
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