Contents:
Foreword: Alan S. Gurman, Ushering in a New Era. Preface: Thomas L. Sexton, Gerald Weekes, Michael S. Robbins, A New Era of Couple and Family Therapy. Part 1: Understanding Families and Couples: The Foundations of Practice. Dorothy S. Becvar, Eras of Epistemology: A Survery of Family Therapy. Michael S. Robbins, Carla C. Mayorga, Jose Szapocznik, The Wcosystem "lens" to Understanding Family Functioning. Celia Jaes Falicov, Ethnicity and Culture in Family Therapy: New Variations on a Fundamental Theme. Part 2: Major Theoretical Models of Couple and Family Therapy. Jill Scharff, Object-relations and Psychodynamic Approaches to Couple and Family Therapy. William C. Nichols, Family of Origin Treatment. Barry L. Duncan, Scott D. Miller, Jacqueline A. Sparks, International Solution Focused Brief Therapies: Evolving Concepts of Change. Harlene Anderson, Postmodern Social Construction Therapies. Frank M. Dattilio, Cognitive-behavioral Couple and Family Therapy. Victoria Behar Mitrani, Structural-Strategic Approaches to Couple and Family Therapy. Jay Lebow, Integrative Approaches to Couple and Family Therapy. Part 3: Evidence Based Couple and Family Intervention Programs. Thomas L. Sexton, Michael S. Robbins, Amy S. Hollimon, Alyson L. Mease, Carla C. Mayorga, Efficacy, Effectiveness, and Change Mechanisms in Couple and Family Therapy. Susan Johnson, Emotionally-Focused Couples Therapy: Empiricism and Art. David Atkins, Sona Dimidjian, Andrew Christesen, Behavioral Couple Therapy: Past Present and Future. Scott Henggler, Sonja K. Schoenwald, Multisystemic Therapy. Thomas L. Sexton, James F. Alexander, Functional Family Therapy: A Mature Clinical Model for Working with At-risk Adolescents and Their Families. Part 4: Special Applications/Special Populations. S. Michael Plaut, Karen Donahey, Evaluation and Treatment of Sexual Dysfunction. Nancy Breen Ruddy, Susan McDaniel, Medical Family Therapy. Timothy J. Ozechowski, Holly Waldron, The Treatment of Adolescent Conduct Disorders and Drug Abuse. Luciano L'Abate, Treatment through Writing. Rita DeMaria, Psychoeducation and Enrichment: Clinincal Considerations for Couple and Family Therapy. Part 5: The Future of Couple and Family Therapy. Thomas L. Sexton, Gerald R. Weeks, Michael S. Robbins, The Future of Couple and Family Therapy.

This detailed volume explores a variety of cutting-edge techniques used to interrogate spatial genome organization. Beginning with a section covering the vital chromosome conformation capture (3C) technique, this collection continues with chapters on targeted Hi-C approaches, sequencing-based approaches to assess nuclear environment, as well as single-cell technologies to better characterize the heterogeneity and dynamics of nuclear architectures and approaches to visualize them by microscopy. Finally, in order to be able to ask functional questions about the role of spatial chromatin organization in genomic control, the last section provides methods for acute manipulations of chromatin architecture. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Spatial Genome Organization: Methods and Protocols is an ideal resource for researchers searching for the best techniques to address their own specific research questions.

This detailed volume explores a variety of cutting-edge techniques used to interrogate spatial genome organization. Beginning with a section covering the vital chromosome conformation capture (3C) technique, this collection continues with chapters on targeted Hi-C approaches, sequencing-based approaches to assess nuclear environment, as well as single-cell technologies to better characterize the heterogeneity and dynamics of nuclear architectures and approaches to visualize them by microscopy. Finally, in order to be able to ask functional questions about the role of spatial chromatin organization in genomic control, the last section provides methods for acute manipulations of chromatin architecture. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.  Authoritative and practical, Spatial Genome Organization: Methods and Protocols is an ideal resource for researchers searching for the best techniques to address their own specific research questions.

This all-new collection by former Alaska poet laureate Tom Sexton smoothly blends his life in Maine, his years in Alaska, and his love of Chinese poetry - which has been a key influence on his work - into a lyrical fantasy that will enchant lovers of verse. These tightly rhythmic, compact eight-line poems demonstrate a rare deftness with - and an even more uncommon ear for - language, revealing poetic form to be neither a puzzle nor an accomplishment in itself, but a compositional tool and a spur to creativity.