This book constitutes the refereed joint proceedings of the First International Workshop on Machine Learning in Clinical Neuroimaging, MLCN 2018, the First International Workshop on Deep Learning Fails, DLF 2018, and the First International Workshop on Interpretability of Machine Intelligence in Medical Image Computing, iMIMIC 2018, held in conjunction with the 21st International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2018, in Granada, Spain, in September 2018. The 4 full MLCN papers, the 6 full DLF papers, and the 6 full iMIMIC papers included in this volume were carefully reviewed and selected. The MLCN contributions develop state-of-the-art machine learning methods such as spatio-temporal Gaussian process analysis, stochastic variational inference, and deep learning for applications in Alzheimer's disease diagnosis and multi-site neuroimaging data analysis; the DLF papers evaluate the strengths and weaknesses of DL and identify the main challenges in the current state of the art and future directions; the iMIMIC papers cover a large range of topics in the field of interpretability of machine learning in the context of medical image analysis.

This book constitutes the refereed proceedings of the Second International Workshop on Context-Aware Surgical Theaters, OR 2.0 2019, and the Second International Workshop on Machine Learning in Clinical Neuroimaging, MLCN 2019, held in conjunction with MICCAI 2019, in Shenzhen, China, in October 2019. For OR 2.0 all 6 submissions were accepted for publication. They aim to highlight the potential use of machine vision and perception, robotics, surgical simulation and modeling, multi-modal data fusion and visualization, image analysis, advanced imaging, advanced display technologies, human-computer interfaces, sensors, wearable and implantable electronics and robots, visual attention models, cognitive models, decision support networks to enhance surgical procedural assistance, context-awareness and team communication in the operating theater, human-robot collaborative systems, and surgical training and assessment. MLCN 2019 accepted 6 papers out of 7 submissions for publication. They focus on addressing the problems of applying machine learning to large and multi-site clinical neuroimaging datasets. The workshop aimed to bring together experts in both machine learning and clinical neuroimaging to discuss and hopefully bridge the existing challenges of applied machine learning in clinical neuroscience.