In this issue of Surgical Oncology Clinics, guest editor Dr. Traci L. Hedrick brings her considerable expertise to the topic of Colorectal Cancer. Excluding skin cancers, colorectal cancer remains the third most common cancer diagnosed in both men and women in the United States. In this issue, top experts in the field provide current discussions on surgery of rectal cancer, colon cancer, targeted therapies, technological advances, genetics of colorectal cancer, and health disparities. Contains 12 relevant, practice-oriented topics including preoperative staging and evaluation of colorectal cancer; technological advances in the surgical treatment of colorectal cancer; surgical principles of rectal cancer; targeted therapy for colorectal cancer; surgical principles of colon cancer; molecular genetics of colorectal cancer/hereditary colorectal cancer syndromes; and more. Provides in-depth clinical reviews on colorectal cancer, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.