Wastewater treatment plants are large non-linear systems subject to large perturbations in wastewater flow rate, load and composition. Nevertheless these plants have to be operated continuously, meeting stricter and stricter regulations. Many control strategies have been proposed in the literature for improved and more efficient operation of wastewater treatment plants. Unfortunately, their evaluation and comparison - either practical or based on simulation - is difficult. This is partly due to the variability of the influent, to the complexity of the biological and biochemical phenomena and to the large range of time constants (from a few minutes to several days). The lack of standard evaluation criteria is also a tremendous disadvantage. To really enhance the acceptance of innovative control strategies, such an evaluation needs to be based on a rigorous methodology including a simulation model, plant layout, controllers, sensors, performance criteria and test procedures, i.e. a complete benchmarking protocol. This book is a Scientific and Technical Report produced by the IWA Task Group on Benchmarking of Control Strategies for Wastewater Treatment Plants. The goal of the Task Group includes developing models and simulation tools that encompass the most typical unit processes within a wastewater treatment system (primary treatment, activated sludge, sludge treatment, etc.), as well as tools that will enable the evaluation of long-term control strategies and monitoring tasks (i.e. automatic detection of sensor and process faults). Work on these extensions has been carried out by the Task Group during the past five years, and the main results are summarized in Benchmarking of Control Strategies for Wastewater Treatment Plants. Besides a description of the final version of the already well-known Benchmark Simulation Model no. 1 (BSM1), the book includes the Benchmark Simulation Model no. 1 Long-Term (BSM1_LT) - with focus on benchmarking of process monitoring tasks - and the plant-wide Benchmark Simulation Model no. 2 (BSM2). Authors: Krist V. Gernaey, Technical University of Denmark, Lyngby, Denmark, Ulf Jeppsson, Lund University, Sweden, Peter A. Vanrolleghem, Universite Laval, Quebec, Canada and John B. Copp, Primodal Inc., Hamilton, Ontario, Canada

International law is an underdeveloped branch of legal research: researchers still disagree over the proper understanding of several of its most fundamental issues, and genuinely so. This book helps to explain why. It brings clarity that will no doubt make international legal research more rational, which in turn vouches for a more productive legal discourse. The author, together with invited contributors, builds an argument around theories of epistemological justification. As chapters contend, in international legal discourse, the construction of knowledge about international law presupposes some notion of an international legal system. International legal discourse accommodates several such notions. Each notion derives from a different conception of law. Thus, depending on whether a researcher endorses a legal positivist's, a legal idealist's or a legal realist's conception of law, he or she will be constructing knowledge of international law under different epistemic conditions. The book sheds considerable light on these different conditions, with several chapters exploring how the different notions of an international legal system play out in the context of a series of concrete themes of legal practice. In doing so, the book helps to build a bridge between the practical and more philosophical aspects of this topic. This book will be an ideal companion for scholars of international law. Lawyers and students interested in legal theory and philosophy will also benefit from this thought-provoking study.

Presenting pragmatist humanism as a form of anti-authoritarianism, this book sheds light on the contemporary significance of pragmatist aesthetics and the revival of humanism. This interdisciplinary study shows that a mediation between pragmatist aesthetics – which emphasizes the significance of creating, making, and inventing – and Marxist materialist aesthetics – which values form – promises interesting results and that the former can learn from the latter. In doing so, Ulf Schulenberg discusses 3 layers of the multi-layered phenomenon that is the revival of humanism: He first explains the potential of a pragmatist humanism, clarifying the contemporary significance of humanism. He then argues that pragmatist humanism is a form of anti-authoritarianism. Finally, he shows the possibility of bringing together the resurgence of humanism and a renewed interest in the work of aesthetic form by arguing that pragmatist aesthetics needs a more complex conception of form. Establishing a transatlantic theoretical dialogue, Humanism, Anti-Authoritarianism, and Literary Aesthetics brings together literary and aesthetic theory, philosophy, and intellectual history. It discusses a broad range of authors – from Emerson, Whitman, James, Nietzsche, Proust, and Dewey to Wittgenstein, Lukács, Adorno, Jameson, Latour, and Rorty – to illuminate how humanism, pragmatism, and anti-authoritarianism are interlinked.

Friedrich Froebel, the ‘father of kindergarten’, is one of the most influential pedagogues of the 19th century. However, relatively little is known about his life, his successes and failures, and his personal relationships. Based on many untranslated and unknown letters, this new biography presents Froebel as a brilliant but also flawed man. Beginning with his childhood and the early death of his mother, as well as his difficult relationship with his father and stepmother, we see the early seeds of Froebel’s interest in children and the training of early childhood practitioners. While Froebel lacked basic academic knowledge due to his poor early education, he was able to overcome these deficits and found an educational institute, and develop ground-breaking educational theories about play and pedagogy. He authored multiple books, including his most famous work The Education of Man. The focus of this book, though, is not on Froebel’s educational theories but on his complicated relationships with his family, the Keilhau community, and the mother of one of his pupils, Caroline von Holzhausen, whom he called the “rune of his life�. After many personal and professional disappointments, Froebel finally came up with the idea that made him famous until today: kindergarten. In the last decade of his life, he became a salesman of this new idea and worked tirelessly for the establishment of the kindergarten movement. However, when the Prussian government banned kindergarten shortly before his death, Froebel was broken – even if kindergarten lives until today.

Sweden is one of a handful of countries where the international arbitral process has reached a stage where the jurisprudence is replete with instances involving no local parties at all. In this context of credible neutrality, the Stockholm Chamber of Commerce (SCC) has emerged as a leading global arbitral institution. Whether the matter at issue is a business transaction dispute or a politicized conflict involving obdurate parties, the richness of its body of decided cases manifests the SCC's authority and reliability throughout the converging world of international arbitration.

This companion volume to "Fundamental Polymer Science" (Gedde and Hedenqvist, 2019) offers detailed insights from leading practitioners into experimental methods, simulation and modelling, mechanical and transport properties, processing, and sustainability issues. Separate chapters are devoted to thermal analysis, microscopy, spectroscopy, scattering methods, and chromatography. Special problems and pitfalls related to the study of polymers are addressed. Careful editing for consistency and cross-referencing among the chapters, high-quality graphics, worked-out examples, and numerous references to the specialist literature make "Applied Polymer Science" an essential reference for advanced students and practicing chemists, physicists, and engineers who want to solve problems with the use of polymeric materials.

This proceedings volume highlights the latest research and developments in psychometrics and statistics. It represents selected and peer-reviewed presentations given at the 85th Annual International Meeting of the Psychometric Society (IMPS), held virtually on July 13-17, 2020. The IMPS is one of the largest international meetings on quantitative measurement in education, psychology and the social sciences. It draws approximately 500 participants from around the world, featuring paper and poster presentations, symposiums, workshops, keynotes, and invited presentations. Leading experts and promising young researchers have written the included chapters. The chapters address a wide variety of topics including but not limited to item response theory, adaptive testing, Bayesian estimation, propensity scores, and cognitive diagnostic models. This volume is the 9th in a series of recent works to cover research presented at the IMPS.

This book addresses and highlights the core issues concerning general principles of EU law and their relationship with and impact on private law. With the entry into force of the Lisbon Treaty, the EU Charter of Fundamental Rights became a legally binding source of primary law and highlights, together with the General Principles of EU law, the importance of fundamental rights in the legal system of the Union. This increased visibility means that private parties have begun to rely on fundamental rights arguments in proceedings in front of national courts and Union courts more and more often. Amongst many other issues this development brings important questions relating to the effects of EU fundamental rights on private law to the forefront. After an introductory chapter by the editors the following four overarching themes provide the structure of this book and broadly reflect the approaches discussed in its eighteen essays:; the methodology and theory in the elaboration of new General Principles of EU law; the Constitutionalization of private autonomy in EU law; issues of horizontal direct effect viewed from conceptual, sectoral and remedial perspectives; and the relationship between General Principles and competition law. This book reflects the continuous relevance and the need to re-examine the effects and the status of General Principles of EU law, which have been dealt with already twice before (in 1999 and 2007) by the group that has compiled the present volume,the Swedish Network for European Legal Studies. The discussion that emerges is, here as before, of immense significance both for theoretical legal studies and for legal practice. The eighteen essays here printed are all final author-edited versions of papers first presented at the Network's conference in Stockholm in November 2012. The authors include both eminent, well-known experts, and representatives of a new generation of younger scholars in the field.

This proceedings volume highlights the latest research and developments in psychometrics and statistics. It represents selected and peer reviewed presentations given at the 84th Annual International Meeting of the Psychometric Society (IMPS), organized by Pontificia Universidad Catolica de Chile and held in Santiago, Chile during July 15th to 19th, 2019. The IMPS is one of the largest international meetings on quantitative measurement in education, psychology and the social sciences. It draws approximately 500 participants from around the world, featuring paper and poster presentations, symposiums, workshops, keynotes, and invited presentations. Leading experts and promising young researchers have written the included chapters. The chapters address a large variety of topics including but not limited to item response theory, multistage adaptive testing, and cognitive diagnostic models. This volume is the 8th in a series of recent volumes to cover research presented at the IMPS.

Every person who encounters or learns another language is faced with the challenge of processing many new words in a short period of time. What are the conditions under which a learner can acquire those words successfully and process them to long-term memory? How do language and memory faculties interact? What role do the senses play in this process? Are factors such as age or individual backgrounds of learners to be considered? Taking the reader on a fascinating journey through the brain to demonstrate how language is processed, Ulf Schutze explains the dynamic environment involved in recording and producing words. The book also discusses how to use information technology, such as Apps, to make the learning of words entertaining and efficient.

In this entertaining account of the origins of modern molecular biology, the lives of pioneering scientists in the field of nucleic acid research, and the discovery of DNA, Ulf Lagerkvist speaks not only to scientists but to all students and general readers with an interest in science. The author, whose career in the nucleic acid field began in the late 1940s, recreates historical episodes from the nineteenth and early twentieth centuries and introduces for a modern audience the scientists whose discoveries revolutionized the field of biology. Knowledge of these pioneers as professionals and as human beings, Lagerkvist believes, may help us see modern problems in a new light and appreciate the greatness of the researchers who contributed to the foundations of molecular biology and biochemistry. Among these scientific pioneers was nineteenth-century biochemist Friedrich Miescher, discoverer of nuclein, the material now known as DNA. The book also explores early research into general problems of the chemistry of biological materials. Lagerkvist vividly describes the research of such influential scientists as Albrecht Kossel, another early leading figure; Emil Fischer, who received the Nobel Prize in 1902 for his work on carbohydrates and purines and was regarded as the foremost chemist of his time; P. A. Levene, known for his discoveries concerning the structure of nucleotides and the way these nucleic acid building blocks are linked to one another; and Oswald T. Avery, often considered the grandfather of molecular genetics.

News of secret Nazi treachery to exterminate the Jews leaks out from the Auschwitz death camp and reaches Koszalin, a Polish ghetto, by way of a clever signal. Five brave leaders devise a plan to undertake a dangerous smuggling operation. They cannot accomplish the feat on their own and must rely on those who are sympathetic to their plight.

One of these supporters is Captain Jay, a daring Polish fisherman. He outwits a Nazi boarding patrol on the high seas, thus beginning a series of historic and desperate escapes late in World War II. His role consists of shuttling groups of refugees to the Danish island of Bornholm, where they are guided across the island to another fishing boat, this one destined for Sweden.

The Danish Resistance, led by Hans, is quick to find the mental weaknesses of the Nazis and exploit them. This quick-thinking Resistance leader falls in love with Rachel, one of the Koszalin refugees who chooses to join the Danish Resistance to fight the tyranny of the Nazis.
Action intensifies both on land and sea with lethal confrontations, as well as a near fatal resolution of a love triangle.

This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities. The book introduces scientists to all of the prerequisites that must be properly addressed, including identification of the right target, specific traits of target binding antibodies, proper selection of the toxic payload, internalization induced by binding, and next generation conjugation and linker technologies. These knowledge-based, revolutionary new drug principles will form the cornerstone of the future standard of care and will lead to major advances in application, as well as improved quality of life and patient survival rates. This book will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology.

This highly practical and self-contained guidebook explains the principles and major applications of digital hologram recording and numerical reconstruction (Digital Holography). A special chapter is designated to digital holographic interferometry with applications in deformation and shape measurement and refractive index determination. Applications in imaging and microscopy are also described. Spcial techniques such as digital light-in-flight holography, holographic endoscopy, information encrypting, comparative holography, and related techniques of speckle metrology are also treated

This volume guides readers through the field of systems medicine by defining the terminology, and describing how established computational methods form bioinformatics and systems biology can be taken forward to an integrative systems medicine approach. Chapters provide an outlook on the role that systems medicine may or should play in various medical fields, and describe different facets of the systems medicine approach in action. Ultimately it introduces tools, resources and methodologies from bioinformatics and systems biology, and how to apply these in a systems medicine project. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, and discuss experimental and computational approaches, methods, and tools that should be considered for a successful systems medicine project. Systems Medicine aims to motivate and provide guidance for collaborations across disciplines to tackle today's challenges related to human health and well-being.

This book approaches post-truth and relativism in a multidisciplinary fashion. Researchers from astrophysics, philosophy, psychology, media studies, religious studies, anthropology, social epistemology and sociology discuss and analyse the impact of relativism and post-truth both within the academy and in society at large. The motivation for this multidisciplinary approach is that relativism and post-truth are multifaceted phenomena with complex histories that have played out differently in different areas of society and different academic disciplines. There is hence a multitude of ways in which to use and understand the concepts and the phenomena to which they refer, and a multitude of critiques and defenses as well. No single volume can capture the ongoing discussions in different areas in all their complexity, but the different chapters of the book can function as exemplifications of the ramifications these phenomena have had.