This volume explores the quickly evolving field of Purinergic signaling, and examines how receptors for ATP and other nucleotides, and receptors for adenosine, act in neuronal transmission, control of synaptic activity, proliferation, differentiation and cell death regulation in the CNS. This book focuses on the participation of purinergic receptors and ectonucleotidases, degrading ATP into adenosine, in embryonic and adult neurogenesis in vitro and in vivo as well as in synaptic transmission and pathophysiology. Further, the chapters discuss varying brain diseases, including Parkinson’s, and Alzheimer’s disease, autism, mood disorders and epilepsy, as well as brain tumors, in the context of purinergic signaling and its clinical aspects. The development of purinergic receptor agonists is also an important issue of this book. This book provides a critical review of the current state of science and will be useful for both scientists and students who are or would like to get involved in this area. Furthermore, this book addresses neuroscientists, physician and professionals from the industry, who would like to update themselves in this exciting and rapidly growing field of neuroscience.

Many books have been published about Japanese motorcycles, but none has focused exclusively on the Japanese motorcycle-based chopper, bobber, trike, and quad custom bike scene--until now.

This book looks at some of the fascinating custom projects out there, accompanied by stunning photography of the finished bikes. A great book for Japanese bike fans, and fans of the custom bike scene in general.

Dieses Lehrbuch tragt der Tatsache Rechnung, dass in der volkswirtschaftlichen Forschung und Beratung neben dem Systemvergleich als Partialvergleich und dem Vergleich wirtschaftlicher Phanomene der wirtschaftspolitische und der problemorientierte Vergleich zunehmend an Bedeutung gewinnen. Es versteht sich als Darstellung der Vergleichsformen und als praktische Anleitung zur eigenstandigen Erstellung und Kritik von Vergleichen. In der zweiten Auflage wurde das Lehrbuch um das Kapitel "Vergleichen der Vergleichsarten" und ein weiteres mit Lernfragen und Ubungsaufgaben erweitert."

Die Deutschen werden immer alter und immer weniger. Die Folgen fur Wirtschaft und Gesellschaft sind dramatischer als die der Wiedervereinigung. Angesichts des demographischen Wandels in den Industriegesellschaften wird eine Alterspolitik erforderlich, die mehr als eine Sozialpolitik fur altere Menschen darstellt. Der von den Autoren vorgestellte Ansatz behandelt die zentralen Fragen und Probleme aus einer interdisziplinaren Sicht. In den einleitenden Kapiteln werden sowohl die demographischen Aspekte des Alterungsprozeses als auch die sozio-okonomischen Folgen des demographischen Wandels erortert. Im Kapitel "Eine"

Bonart/Peters fuhren mit Hilfe mathematischer Modelle systematisch in die grundlegenden Fragen der Mikrookonomie ein. Der Stoff jedes Kapitels wird durch Aufgaben gezielt vertieft. Durch integrierte Losungshinweise eignet sich dieses Lehrbuch auch ausgezeichnet zum Selbststudium.

DJD XXXII presents the first full critical edition of the Great Isaiah Scroll (1QIsa]a) and the Hebrew University Isaiah Scroll (1QIsa]b), which constitute almost 30% of all the preserved biblical material, in the styles of the DJD series. That is, whereas the photographs and transcriptions have been available since the 1950s, this volume provides a fresh transcription of all the known fragments, notes clarifying problematic readings, and the first comprehensive catalogue of the textual variants. It is not, and cannot be, a comprehensive analysis of all these highly influential manuscripts, on which innumerable studies have been published over the past half century. Part 1 contains the photographic plates (1QIsa]a in colour) with the transcriptions on facing pages for easy comparison. Part 2 contains the introductions, notes, and catalogue of variants. The main introduction narrates the discovery and early history of these two manuscripts.

DJD XXXII presents the first full critical edition of the Great Isaiah Scroll (1QIsa]a) and the Hebrew University Isaiah Scroll (1QIsa]b), which constitute almost 30% of all the preserved biblical material, in the styles of the DJD series. That is, whereas the photographs and transcriptions have been available since the 1950s, this volume provides a fresh transcription of all the known fragments, notes clarifying problematic readings, and the first comprehensive catalogue of the textual variants. It is not, and cannot be, a comprehensive analysis of all these highly influential manuscripts, on which innumerable studies have been published over the past half century. Part 1 contains the photographic plates (1QIsa]a in colour) with the transcriptions on facing pages for easy comparison. Part 2 contains the introductions, notes, and catalogue of variants. The main introduction narrates the discovery and early history of these two manuscripts.