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Every year dozens of physicians-in-training face, for the first
time, the responsibil ity of examining and diagnosing central
nervous system tumors or biopsies of the central nervous system,
the peripheral nerves or muscles, whose surgical resection has been
decided on both as a form of treatment (in the case of tumors) and
as means to confirm a presumptive diagnosis. The selection of the
most appropriate form of post surgical treatment for most tumors is
predicated on the precise identification of the tumor cells. The
evaluation of the specimen, by a pathologist, will not only
determine whether the lesion is truly neoplastic, but also whether
there are histologic indicators of malig nancy. Moreover, in some
cases, the pathologist will be asked to determine whether the tumor
cells contain certain hormone precursors or receptors, as an
example. Recognition of many of the features that one must search
for requires the judicious application of methods that may not be
readily known to the physicians involved in the various diagnostic
procedures. The handling and processing of the tissues as they
arrive in the pathology laboratory for the above reasons vary as a
function of the organ (or site) of origin of a given tumor as well
as a function of the presumptive clinical diagnosis. The material
contained in this book series has been organized in an attempt to
help the pathologists-in-training, the general pathologists, the
neurosurgeons, and neu rologists to understand the logic behind
such special requirements."
From the preface: "Pathologists are responsible for the
interpretation of tissue samples removed for the purpose of
establishing a diagnosis. This textbook has been conceived and
arranged in a manner that facilitates the task of arriving at a
diagnosis through the evaluation of tissues removed from patients
afflicted with neurological complaints. The portion of the
diagnostic work-up that is purely "clinical", such as the history
of the disease and the results of the physical examination are
entirely beyond the scope of this textbook...Extensive descriptions
of disease processes, which are available in most of the references
cited, have been omitted in favor of relatively detailed
descriptions and abundant illustrations of the histologic
abnormalities that, as a group, constitute a diagnostic entity."
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