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Modern surgical oncology is characterized by multimodal therapy. In
recent years numerous therapeutic approaches of pre-, peri-,
intra-and postoperative treatment have been in vestigated with
regard to their use in combination with surgi cal intervention. It
now is time to analyze and to define the state of our knowledge.
For tumors of the gastrointestinal tract there are several
encouraging therapeutic approaches, such as preop erative
chemotherapy in esophageal and perioperative chemotherapy in colon
cancer. For some special tumors, like anal carcinoma, we have
clearly defined combined therapies which even now must be viewed as
standard treatment. It is also time to demonstrate the results of
several clini cal studies that have been conducted within the last
few years that combined surgical efforts with pre- or postinter
ventional chemotherapy or radiotherapy. It is necessary to evaluate
whether these trials contribute to progress in onco logical
therapy. The editors of this volume - surgeons at the university
hospitals of Heidelberg and Zurich - must be given the mer it of
achieving these goals. It was especially appropriate for the
Department of Surgery in Heidelberg, in close coopera tion with the
Comprehensive Cancer Center Heidelberg/ Mannheim, to prepare a
review of our present knowledge of surgical oncology as it is in
the tradition of attempting to combine different therapeutic
approaches to cancer therapy.
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