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Nitric oxide, "Molecule of the Year" in 1995, continues to be one
of the most widely studied molecules in brain research. This
excellent volume elucidates the implications of this gas in a
variety of brain processes.
The volume is divided into five sections, describing: the
mechanisms underlying the release and action of Nitric Oxide in the
CNS, and the distribution of Nitric Oxide in the brain using
various techniques; how Nitric Oxide interacts with and regulates
the "N"-methyl-D-aspartate receptor; the role of Nitric Oxide in
pathway refinement and synapse stabilization in the developing CNS;
the role of Nitric Oxide in adult brain plasticity including
long-term potentiation and depression; and the role of Nitric Oxide
in brain injury such as occurs during ischemia and other events
produced by glutamate neurotoxicity, and in neuroprotective
mechanisms that promote neuron survival.
"Nitric Oxide in Brain Development, Plasticity, and Disease" is the
first "Progress in Brain Research" volume to be published in
abstracted form on the World Wide Web. It includes title pages,
abstracts, selected figures, and complete references. It also
includes a digital brain atlas for readers to view a mouse brain in
a three-dimensional full-color rendition, and much more.
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