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This brief offers a comprehensive discussion of magnetic targeted
drug delivery of silica-coated nanodevices. Focusing on the latest
trend in pharmaceutical applications of these nanodevices, a
multidisciplinary overview is displayed, from synthesis and design
to pharmacokenetics, biodistribution and toxicology. Chapters
include design of silica-coated magnetic nanodevices; techniques
for drug loading with features applicable to biological systems;
synthesis, characterization and the assessment of biomedical issues
with both in vitro and in vivo experiments. Applications in the
treatment of different localized diseases are also addressed in
order to present the potential use of these nanosystems as global,
commercially available therapeutics.
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