Biological Membrane Vesicles: Scientific, Biotechnological and Clinical Considerations, Part Two, Volume 33 in the Advances in Biomembranes and Lipid Self-Assembly series, highlights new advances in the field, with sections in this new release covering Biomembranes of extracellular vesicles: The protein component, Protocol for isolation of Microvesicles form blood plasma, Urinary Extracellular vesicles at single patient level for clinical research, Treatment of chronic wounds with platelet and extracellular vesicles enriched plasma, Liposome loading and imaging, The Potential of Extracellular Vesicles for Brain Repair, Nucleic acids cargo of extracellular vesicles: Analysis and physiological function, Propolis flavonoids and terpenes, and much more.

This book is a survey on the theoretical as well as experimental results on nanostructures in biological systems. It shows how a unifying approach starting from single-particle energy, deriving free energy of the system and determining the equilibrium by minimizing the free energy, can be applied to describe electrical and elastic phenomena. It helps the readers to use this basic, transparent, and simple approach to develop additional new systems and interactions and describes the theoretical and experimental aspects together so that they support each other in broadening the knowledge on biological systems. It suggests potential use of this knowledge in clinically relevant phenomena such as hemostasis, inflammation, and spreading of cancer and describes some applications in nanotoxicology, such as the interactions between biological membranes and inorganic nanostructures.

Biological Membrane Vesicles: Scientific, Biotechnological and Clinical Considerations, Part 1 Volume 32 in the Advances in Biomembranes and Lipid Self-Assembly series, highlights new advances in the field, with this release presenting chapters written by an international board of authors. Topics in this new release include Amyloid ss-peptide interaction with GM1 containing model membrane, The Human EV Membranome, Protocol for isolation of Microvesicles form blood plasma, Urinary Extracellular Vesicles: Single patient analysis for clinical applications, Treatment of chronic wounds with platelet and extracellular vesicles enriched plasma, Liposome loading and imaging, Standardization and reproducibility in EV research: the support of a Quality management system, and much more.

The human hip joint is a common site of trauma and disease. Since the disease of the hip joint yields to immobility of the patient a considerable research has been directed toward understanding its development. It is acknowledged that the excessive mechanical loading may induce joint degeneration. The main biomechanical parameters which have been used to determine biomechanical status of the hip are the hip joint reaction force and the contact stress distribution in the hip joint articular surface. This book provides overview of methods that can be used to assess biomechanical variables acting in the human hip joint with emphasis on application of the results in practice. Described mathematical model of the hip joint reaction force is based on the static optimization approach while the hip contact stress distribution is estimated from the elasticity analysis. Mathematical modeling is applied to study normal and dysplastic hips during routine activities and to assess the stress distribution in hips subjected to avascular necrosis of the femoral head.