Advanced IoT based wireless communication has recently received a lot of attention due to a wide range of industry 4.0 applications such as security solutions of CPS in vehicular communication, E_Healthcare over secure wireless communication, privacy issues of E_Learning via cost and energy efficient wireless network communication, etc. In these applications, physical data is continuously monitored by the IoT-based sensor nodes to facilitate the current situations, 5G network management, security solutions, etc. in industry 4.0 environment. Despite the many security issues considered in existing wireless communication in the industry 4.0 applications, IoT based 5G and 5G+ wireless communication will enhance the future security issues including cybersecurity solutions. The aim of this book to deliver the best services with minimum cost and maximum security in all industry 4.0 applications. For instance, medical priority services against the available sources and devices (IoT, sensors, decision-making units, etc.), patient monitoring services against the waiting list and the population, and security services of CPS against the energy efficiency and the battery lifetime are challenging critical problems in the industry 4.0. This book covers some improvement methods in security influence to future communication they are cybersecurity issues of IoT based 5G and 5G+ communication systems. These methods can be considered through the efficient channel coding scheme, efficient traffic management, bandwidth guard, cybersecurity solutions, etc. Requirements for future communication such 5G+ support to illustrate the security issues in selected applications of industry 4.0 such as learning style transformation. Sensors are typically capable of wireless communication and are significantly utilized in many applications such as medical communication with IoT-based 5G infrastructure. Despite many security solutions of communication technologies, decision making, dynamic and intelligent solutions based on sensors, IoT devices, CPS, etc. will be minimizing energy costs and maximizing security issues of industry 4.0. The field of advanced IoT-based 5G+ wireless communication networks merge a lot of functions like secure transmission capacities with latest multiple access schemes, computation of best latency and energy efficiency, and secure communication with location-based services, etc. This book covers many functionalities through the important examples and applications used in industry 4.0.