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Various KLK proteins and their encoding genes have attracted
increased attention among scientists and clinicians worldwide since
they represent very interesting and functionally distinct
biomarkers, particularly, in cancer. This book reviews the role of
kallikrein-related peptidases (KLKs) in a wide range of cancers,
including lung, prostate, breast and ovarian cancer. It provides
clinicians, physician scientists and researchers with a
comprehensive overview on the clinical relevance of KLK expression
in various malignancies.
This handbook is the first comprehensive book of its kind reviewing
the clinically relevant current status of tissue kallikrein and
kallikrein-related peptidases research. Since several members of
the KLK family are key players in (patho-)physiological processes,
structural, functional, and regulatory studies are under way to
develop new strategies to prevent and treat disorders to which
individual members of the KLK protease family contribute
significantly. The goal of this book is to inform clinicians,
physician scientists and researchers about the prominent role of
the multifaceted and interactive KLK system in normal physiology
and pathological organ function.
Various KLK proteins and their encoding genes have attracted
increased attention among scientists and clinicians worldwide since
they represent very interesting and functionally distinct
biomarkers, particularly, in cancer. This book reviews the role of
kallikrein-related peptidases (KLKs) in a wide range of cancers,
including lung, prostate, breast and ovarian cancer. It provides
clinicians, physician scientists and researchers with a
comprehensive overview on the clinical relevance of KLK expression
in various malignancies.
This handbook is the first comprehensive book of its kind reviewing
the clinically relevant current status of tissue kallikrein and
kallikrein-related peptidases research. Since several members of
the KLK family are key players in (patho-)physiological processes,
structural, functional, and regulatory studies are under way to
develop new strategies to prevent and treat disorders to which
individual members of the KLK protease family contribute
significantly. The goal of this book is to inform clinicians,
physician scientists and researchers about the prominent role of
the multifaceted and interactive KLK system in normal physiology
and pathological organ function.
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