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Drug Discovery and Development, Third Edition presents up-to-date
scientific information for maximizing the ability of a
multidisciplinary research team to discover and bring new drugs to
the marketplace. It explores many scientific advances in new drug
discovery and development for areas such as screening technologies,
biotechnology approaches, and evaluation of efficacy and safety of
drug candidates through preclinical testing. This book also greatly
expands the focus on the clinical pharmacology, regulatory, and
business aspects of bringing new drugs to the market and offers
coverage of essential topics for companies involved in drug
development. Historical perspectives and predicted trends are also
provided. Features: Highlights emerging scientific fields relevant
to drug discovery such as the microbiome, nanotechnology, and
cancer immunotherapy; and novel research tools such as CRISPR and
DNA-encoded libraries Case study detailing the discovery of the
anti-cancer drug, lorlatinib Venture capitalist commentary on
trends and best practices in drug discovery and development
Comprehensive review of regulations and their impact on drug
development, highlighting special populations, orphan drugs, and
pharmaceutical compounding Multidiscipline functioning of an
Academic Research Enterprise, plus a chapter on Ethical Concerns in
Research Contributions by 70+ experts from industry and academia
specialists who developed and are practitioners of the science and
business
Drug Discovery and Development, Third Edition presents up-to-date
scientific information for maximizing the ability of a
multidisciplinary research team to discover and bring new drugs to
the marketplace. It explores many scientific advances in new drug
discovery and development for areas such as screening technologies,
biotechnology approaches, and evaluation of efficacy and safety of
drug candidates through preclinical testing. This book also greatly
expands the focus on the clinical pharmacology, regulatory, and
business aspects of bringing new drugs to the market and offers
coverage of essential topics for companies involved in drug
development. Historical perspectives and predicted trends are also
provided. Features: Highlights emerging scientific fields relevant
to drug discovery such as the microbiome, nanotechnology, and
cancer immunotherapy; and novel research tools such as CRISPR and
DNA-encoded libraries Case study detailing the discovery of the
anti-cancer drug, lorlatinib Venture capitalist commentary on
trends and best practices in drug discovery and development
Comprehensive review of regulations and their impact on drug
development, highlighting special populations, orphan drugs, and
pharmaceutical compounding Multidiscipline functioning of an
Academic Research Enterprise, plus a chapter on Ethical Concerns in
Research Contributions by 70+ experts from industry and academia
specialists who developed and are practitioners of the science and
business
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