Covers fundamentals of peptide and protein drug delivery. This reference/text includes such considerations as synthesis, physical chemistry and biochemistry, analysis, proteolytic and transport constraints, pharmacokinetics, and pharmacodynamics as well as bioavailability from routes of administration.

The Systems of the Body series has established itself as a highly valuable resource for medical and other health science students following today's systems-based courses. Now thoroughly revised and updated in this third edition, each volume presents the core knowledge of basic science and clinical conditions that medical students need, providing a concise, fully integrated view of each major body system that can be hard to find in more traditionally arranged textbooks or other resources. Multiple case studies help relate key principles to current practice, with links to clinical skills, clinical investigation and therapeutics made clear throughout. Each (print) volume also now comes with access to the complete, enhanced eBook version, offering easy anytime, anywhere access - as well as self-assessment material to check your understanding and aid exam preparation. The Renal System provides highly accessible coverage of the core basic science principles in the context of clinical case histories, giving the reader a fully integrated understanding of the system and its major diseases. Introduction to the Renal System Body Fluids, Nephron Function and Diuretics Water Balance and Regulation of Osmolality Acid-Base Balance and Regulation of pH Glomerular Filtration and Acute Kidney Injury Proteinuria and the Nephrotic Syndrome Glomerulonephritis and the Acute Nephritic Syndrome Diabetic Nephropathy and Chronic Kidney Disease Kidney Failure and Replacement of Renal Function Hypertension and the Kidney Pregnancy and the Kidney Urinary Tract Obstruction and Stones Renal Masses, Cysts and Urinary Tract Tumours Drugs and the Kidney Systems of the Body Series: The Renal System The Musculoskeletal System The Nervous System The Digestive System The Endocrine System The Respiratory System The Cardiovascular System

It is May 28, 1453 and Constantinople has reached the last day of its existence. Within 24 hours, the 21 year old Ottoman Turk, Sultan Mehmet II will blast through the walls of the city and the Byzantine Empire will cease to exist. Inside the palace, Leif Redbjorn, Captain of a small group of Northmen known as the Varangian Guard prepares his warriors for a final battle. The Varangian Guard has been the Empire's elite mercenary unit for over 500 years; fiercely loyal to the Emperor even unto death. These remaining few are the last of their kind. The warriors of the Varangian Guard are Northmen; mostly Vikings. Some of these Vikings are known as 'Berserkers'. In Viking battles, Berserkers were used as shock troops by the Scandinavian Kings to strike terror in the hearts of their enemies. They would consume wine or ale and work themselves into a blood lust rage or 'Odin Fury' while dancing around a bonfire. Emperor Constantine VII, The Purple Born, called it a 'Gothic Dance'. Captain Redbjorn calls his 14 year old son, Erik to his side and gives him an overwhelming task; "I have a great thing I must ask of you. Go to my chamber. Under the chest at the foot of my bed is a stone with a wolf carved into it. Pry it up and you will find a book that has been passed down through the centuries. It holds the secret of the Varangian Guard; one that was carelessly lost by our ancestors and we have been searching in vain to find it again. You must follow my instructions left within." Soon, Erik Redbjorn will find out for himself what it means to be a Varangian Guard. He will learn why hardened warriors tremble in fear when the drums begin to beat, the bonfire rages into the sky and word spreads that Berserkers are dancing...

"Whilst we can't deny the existence of ladders in life, we should never be so taken over with the desire to climb that we allow it to overcome the desire to be loved and rest on the rungs where we are now. No earthly ladder can ever take us closer to God, only God can draw us closer to Himself." 'Horizontal Ladders' reflects the author's wonderfully colourful and agile mind. Readers should expect the unexpected. From the experiences and joy of the birth of his children, to the struggles of mental health, from the teachings of Genesis, to dealing with the grief of losing a loved one, this is a great collection of God-inspired thoughts. Vince Lee is a Christian father of four wonderful children, husband to an amazing wife and has Rapid Cycling Bipolar Disorder. Since being diagnosed he has spent time in quiet Suffolk, collating many years of writings and poetry to form this book. In characteristically modest fashion, he describes this book as 'random', like him and like life!

ISMS... those things that divide & separate us. SCHISMS... those things that keep us apart & POETIC RHYTHMS... those things that bring us together... puts a smile on our faces and keeps LOVE in our Hearts. A Collection of Poetry Geared Toward the Young and the Old... Combining Old School Values and Wisdom With the Witty Wordplay of Today's Generation. If You Don't Have it, You Need To Get It... Today!