This volume is the outcome of a recent NATO Advanced Study Institute (ASI) on "Technology Assessment. Environmental Impact Assessment. and Risk Analysis: Contributions from the Psychological and Decision Sciences." The Institute was held in Les Arcs. France and functioned as a high level teaching activity during which scientific research results were presented in detail by eminent lecturers. Support for the Institute was provided by grants from the NATO Division of Scientific Affairs. the u.S. Office of Naval Research. and the Russell Sage Foundation. The Institute covered several areas of research. including quantitative studies on decision and judgmental processes. studies on human intellectual limitations. studies on risk attitudes and perceptions. studies on factors contributing to conflicts and disputes about hazardous technologies and activities. studies on factors influencing forecasts and judgments by experts. studies on public preferences for decisionmaking processes. studies on public responses to technological hazards. and case studies applying principles and methods from the psychological and decision sciences in specific settings.

The purpose of this book is to investigate the suitability and applicability of available methods for analyzing the human and ecological risks involved in the release of genetically-modified microorganisms. Main topics include: - risk analysis and assessment; approach to safety assurance; - inventory of available scientific risk assessment methods for biotechnology; - identification of methodology gaps and research needs in biology, ecology or other disciplines; - development of a general framework to guide future biotechnology risk assessment efforts; - international regulatory activities.

The theme of this volume--risk analysis in the private sector--reflects a changing emphasis in risk analysis. Until re cently, attention has been focused on risk analyses conducted in support of federal regulatory decision making. Such analyses have been used to help set safety standards, to illuminate issues of regulatory concern, and to evaluate regulatory alternatives. As this volume indicates, however, risk analysis encompasses a broader set of activities. Analyses performed by private sector institutions aimed at preventing or reducing potential adverse health or environmental effects also play an important part in societal risk management. In virtually all societies, there have been strong incentives for the private sector to conduct such analyses. These incentives range from moral or altruistic norms and values to simple self-interest based on fear of monetary loss, possible civil or criminal litigation, or punitive or restrictive government action. The papers in this volume address the overall theme from a variety of perspectives. Specifically, the papers represent con tributions from such diverse fields as toxicology, epidemiology, chemistry, biology, engineering, statistics, decision analysis, economics, psychology, philosophy, and the law."