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From the Lab to Clinical Settings-Advances in Quantitative,
Noninvasive Optical Diagnostics Noninvasive fluorescence imaging
techniques, novel fluorescent labels, and natural biomarkers are
revolutionizing our knowledge of cellular processes, signaling and
metabolic pathways, the underlying mechanisms for health problems,
and the identification of new therapeutic targets for drug
discoveries. Natural Biomarkers for Cellular Metabolism: Biology,
Techniques, and Applications delves into the current state of
knowledge on intrinsic fluorescent biomarkers and highlights recent
developments in using these biomarkers for the metabolic mapping
and clinical diagnosis of healthy and diseased cells and tissues.
Autofluorescent Biomarkers for Biomedical Diagnostics The book's
first section introduces the fundamentals of cellular energy
metabolism as well as natural biomarkers within the context of
their biological functions. The second section outlines the
theoretical and technical background of quantitative, noninvasive,
autofluorescence microscopy and spectroscopy methods, including
experimental design, calibration, pitfalls, and remedies of data
acquisition and analysis. The last two sections highlight advances
in biomedical and biochemical applications, such as monitoring stem
cell differentiation in engineered tissues and diagnosing cancer
and ophthalmic diseases quantitatively and noninvasively. Tailored
to Interdisciplinary Researchers Covering cell biology, imaging
techniques, and clinical diagnostics, this book provides readers
with a complete guide to studying cellular/tissue metabolism under
healthy, diseased, and environment-induced stress conditions using
natural biomarkers. The book is designed for graduate and advanced
undergraduate students, biophysics instructors, medical
researchers, and those in pharmaceutical R&D.
From the Lab to Clinical Settings-Advances in Quantitative,
Noninvasive Optical Diagnostics Noninvasive fluorescence imaging
techniques, novel fluorescent labels, and natural biomarkers are
revolutionizing our knowledge of cellular processes, signaling and
metabolic pathways, the underlying mechanisms for health problems,
and the identification of new therapeutic targets for drug
discoveries. Natural Biomarkers for Cellular Metabolism: Biology,
Techniques, and Applications delves into the current state of
knowledge on intrinsic fluorescent biomarkers and highlights recent
developments in using these biomarkers for the metabolic mapping
and clinical diagnosis of healthy and diseased cells and tissues.
Autofluorescent Biomarkers for Biomedical Diagnostics The book's
first section introduces the fundamentals of cellular energy
metabolism as well as natural biomarkers within the context of
their biological functions. The second section outlines the
theoretical and technical background of quantitative, noninvasive,
autofluorescence microscopy and spectroscopy methods, including
experimental design, calibration, pitfalls, and remedies of data
acquisition and analysis. The last two sections highlight advances
in biomedical and biochemical applications, such as monitoring stem
cell differentiation in engineered tissues and diagnosing cancer
and ophthalmic diseases quantitatively and noninvasively. Tailored
to Interdisciplinary Researchers Covering cell biology, imaging
techniques, and clinical diagnostics, this book provides readers
with a complete guide to studying cellular/tissue metabolism under
healthy, diseased, and environment-induced stress conditions using
natural biomarkers. The book is designed for graduate and advanced
undergraduate students, biophysics instructors, medical
researchers, and those in pharmaceutical R&D.
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