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Originally published in 1992, this volume looks in detail at the
important relationship, initially studied in 1871 by Bowditch,
between the strength of the heartbeat and the interval between
beats. The book draws together the work and experience of leading
international research workers in this field. Collectively, the
contributors illuminated the underlying mechanisms involved, their
expression in both isolated muscle and the intact heart, and
speculate on further avenues of research. The volume will be of
interest to cardiologists, physiologists and all those concerned
with the function of the heart.
Continuing demand for this book confirms that it remains relevant
over 30 years after its first publication. The fundamental
explanations are largely unchanged, but in the new introduction to
this second edition the authors are on hand to guide the reader
through major advances of the last three decades. With an emphasis
on physical explanation rather than equations, Part I clearly
presents the background mechanics. The second part applies
mechanical reasoning to the component parts of the circulation:
blood, the heart, the systemic arteries, microcirculation, veins
and the pulmonary circulation. Each section demonstrates how an
understanding of basic mechanics enhances our understanding of the
function of the circulation as a whole. This classic book is of
value to students, researchers and practitioners in bioengineering,
physiology and human and veterinary medicine, particularly those
working in the cardiovascular field, and to engineers and physical
scientists with multidisciplinary interests.
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