Authored by the world's foremost stroke experts, this classic text brings you fully up to date with current research findings and management approaches for cerebrovascular disease. Stroke: Pathophysiology, Diagnosis, and Management, 7th Edition, covers every aspect of this fast-moving field, and is an ideal resource for stroke specialists, general neurologists, and other medical professionals with an interest in stroke. You'll find expert clinical guidance, comprehensive pathophysiology coverage, data from recent trials, advances in diagnostic tests, full-color CT images, pathology slides, and much more, for a complete picture of today's stroke medicine. Helps you recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Keeps you abreast of the overwhelming volume of studies and guidelines in this dynamic field, providing clear summaries and practical evaluations of all relevant data. Contains updates throughout, including the latest clinical trials (thrombectomy, DAWN, DEFUSE), genetics research, prevention research, new therapies, and the new guidelines from the ASA. Includes new slides for lectures, covering basic science, case studies, and interventional treatment overviews. Features a Key Points summary at the beginning of each chapter so you can quickly find important information. Provides abundant full-color CT images and pathology slides that help you make efficient and accurate diagnoses. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This book, the second of three volumes, concentrates on peripheral nervous system disorders. Examining the effects of neurotoxicants on nerve, muscle and the neuromuscular junction, it builds on the scientific principles outlined in volume 1 by looking at the application of the methods discussed, particularly in terms of the evaluation and diagnosis of individual patients and the related process of establishing causation. Neurobehavorial Toxicology, Volume 2 will be of interest to practicing neurologists and neuropsychologists, as well as to occupational medicine physicians and medical toxicologists.

This book, the first of three volumes, provides a thorough background to the emerging field of neurobehavioral toxicology by looking at current clinical approaches and tests, as well as assessing current clinical research. The analysis of the impact of toxins on the human nervous system is particularly pertinent given the ongoing expansion of pharmaceuticals, industrial hazards, biological warfare and global pollution. A comprehensive introduction to neurobehavioral toxicology, this work will be of interest to practicing neurologists and neuropsychologists, as well as to occupational medicine physicians and medical toxicologists.

This book, the first of three volumes, provides a thorough background to the emerging field of neurobehavioral toxicology by looking at current clinical approaches and tests, as well as assessing current clinical research. The analysis of the impact of toxins on the human nervous system is particularly pertinent given the ongoing expansion of pharmaceuticals, industrial hazards, biological warfare and global pollution.

A comprehensive introduction to neurobehavioral toxicology, this work will be of interest to practicing neurologists and neuropsychologists, as well as to occupational medicine physicians and medical toxicologists.

This is the final volume in a three-volume work that has addressed the scientific methodologies relevant to clinical neurobehavioral toxicology. Volume I focused on basic concepts and methodologies in Neurobehavioral Toxicology, with Volume II focusing on the peripheral nervous system. Volume III attends to what is known about industrial and environmental chemicals, medicines, and substances of abuse and how these agents affect the central nervous system. All substances have the capacity to be toxic, depending on factors that include the physical properties of the chemical or compound, organism related variables, or interaction between the two. These substances on the other hand and as a result of these same factors might be used therapeutically or even recreationally. The difference between medicine, recreational drug, or poison depends often on a careful balance between adverse and intended effects. How to determine that a specified substance has caused harm is emphasized in the present volume by way of case examples and discussion. Illnesses and behavioral variations that compete with toxicant-induced explanations for findings in a given case, as well as the various controversies that can arise around issues of diagnosis and causal determination, are treated comprehensively in this volume.

This is the final volume in a three-volume work that has addressed the scientific methodologies relevant to clinical neurobehavioral toxicology. Volume I focused on basic concepts and methodologies in Neurobehavioral Toxicology, with Volume II focusing on the peripheral nervous system. Volume III attends to what is known about industrial and environmental chemicals, medicines, and substances of abuse and how these agents affect the central nervous system. All substances have the capacity to be toxic, depending on factors that include the physical properties of the chemical or compound, organism related variables, or interaction between the two. These substances on the other hand and as a result of these same factors might be used therapeutically or even recreationally. The difference between medicine, recreational drug, or poison depends often on a careful balance between adverse and intended effects. How to determine that a specified substance has caused harm is emphasized in the present volume by way of case examples and discussion. Illnesses and behavioral variations that compete with toxicant-induced explanations for findings in a given case, as well as the various controversies that can arise around issues of diagnosis and causal determination, are treated comprehensively in this volume.

A social dilemma is a game which at first glance has only inefficient solutions. If efficient solutions are to be achieved, some kind of cooperation among the players is required. This book asks two basic questions, closely intertwined with each other: 1. How is cooperation possible among rational players in such a social dilemma? Which changes in the social context of a social dilemma situation are necessary in order for players to rationally choose the cooperative option? 2. How do real players actually behave in social dilemma situations? Do they behave "rationally" at all? Or, conversely, what kind of reasoning, attitudes, emotions, etc. shape the behavior of real players in social dilemmas? What kind of interventions, what kind of internal mechanisms within a real group may change players' willingness to cooperate? These two general questions mark the broad spectrum of the problem which has been, over the last three decades, investigated in various disciplines, and which has brought many new ideas and new observations into the study of the old question of social order in a world of born egoists. Accordingly, this volume contains contributions by biologists, sociologists, political scientists, economists, mathematicians, psychologists, and philosophers.

This paper represents the collaborative work of a game theorist and a policy analyst in an attempt to examine severa! questions that go to the hearl of the way individuala achieve social order. The capacity of any individual to undertake long-term, productive activities that affect and are affected by the actiona of other individuala dependa upon gaining a minimallevel of predictability among those involved. No one could successfully drive to work if the behavior of other drivera were noi relatively predictable. No one could operate a stare, if potential consumers did not purcha. se, rather than stea!, the commodities offered to the public. No one would ma. ke a. ny investments other than those tha. t would be made by a solitary individual in an isolated setting (the cla. ssic Robinson Crusoe situation). One of the ways that individuals achieve predictability in social arrangements is to a. gree to follow a set of normative prescriptions a. bout what they must, must not, or may do. Agreeing to a set of prescriptions is relatively easy. Actually following those prescriptions over time when temptations arise offering potentially high payoffs, is not at all easy. In natural settings, individUala follow agreed upon prescriptions to a greater or lesser extent depending on enforcement levels. A frequent assumption made by policy ana. lysts a. nd game theorists is tha. t enforcement is externa! to the situa. tion under analysis. That a.

The four volumes of Game Equilibrium Models present applications of non-cooperative game theory. Problems of strategic interaction arising in biology, economics, political science and the social sciences in general are treated in 42 papers on a wide variety of subjects. Internationally known authors with backgrounds in various disciplines have contributed original research. The reader finds innovative modelling combined with advanced methods of analysis. The four volumes are the outcome of a research year at the Center for Interdisciplinary Studies of the University of Bielefeld. The close interaction of an international interdisciplinary group of researchers has produced an unusual collection of remarkable results of great interest for everybody who wants to be informed on the scope, potential, and future direction of work in applied game theory. Volume III Strategic Bargaining contains ten papers on game equilibrium models of bargaining. All these contributions look at bargaining situations as non-cooperative games. General models of two-person and n-person bargaining are explored.

This paper represents the collaborative work of a game theorist and a policy analyst in an attempt to examine severa! questions that go to the hearl of the way individuala achieve social order. The capacity of any individual to undertake long-term, productive activities that affect and are affected by the actiona of other individuala dependa upon gaining a minimallevel of predictability among those involved. No one could successfully drive to work if the behavior of other drivera were noi relatively predictable. No one could operate a stare, if potential consumers did not purcha. se, rather than stea!, the commodities offered to the public. No one would ma. ke a. ny investments other than those tha. t would be made by a solitary individual in an isolated setting (the cla. ssic Robinson Crusoe situation). One of the ways that individuals achieve predictability in social arrangements is to a. gree to follow a set of normative prescriptions a. bout what they must, must not, or may do. Agreeing to a set of prescriptions is relatively easy. Actually following those prescriptions over time when temptations arise offering potentially high payoffs, is not at all easy. In natural settings, individUala follow agreed upon prescriptions to a greater or lesser extent depending on enforcement levels. A frequent assumption made by policy ana. lysts a. nd game theorists is tha. t enforcement is externa! to the situa. tion under analysis. That a.

The four volumes of Game Equilibrium Models present applications of non-cooperative game theory. Problems of strategic interaction arising in biology, economics, political science and the social sciences in general are treated in 42 papers on a wide variety of subjects. Internationally known authors with backgrounds in various disciplines have contributed original research. The reader finds innovative modelling combined with advanced methods of analysis. The four volumes are the outcome of a research year at the Center for Interdisciplinary Studies of the University of Bielefeld. The close interaction of an international interdisciplinary group of researchers has produced an unusual collection of remarkable results of great interest for everybody who wants to be informed on the scope, potential, and future direction of work in applied game theory. Volume III Strategic Bargaining contains ten papers on game equilibrium models of bargaining. All these contributions look at bargaining situations as non-cooperative games. General models of two-person and n-person bargaining are explored.

This comprehensive introduction to the developing field of neurobehavioral toxicology, offers an extensive evaluation of the ways in which toxins affect the human nervous system and behavior. It combines two fields of expertise, neurology and neuropsychology, both of which are founded on the assessment and treatment of the nervous system in health and disease, to consider the ways in which substances impact on the human body. It includes detailed analysis of individuals with neurological or neurobehavioral disorders and considers how these may be attributable to neurotoxicants. It also addresses and critiques the scientific methodologies relevant to developing a clinical diagnosis of these disorders and their etiologies. This book, the second of three volumes, concentrates on peripheral nervous system disorders.