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The study of disease entities as complex as Crohn's dis ease will
increasingly require comprehensive knowledge of formerly unrelated
areas of the medical sciences. To promote this broad approach, a
conference was organized in which geneticists, morphologists,
immunologists, and virologists participated as well as clinicians
whose work is focused on Crohn's disease. Ample time was given to
the presentation of major new findings in each of these areas, and
comments were given by the participants in the various sections.
This approach yielded many new ideas, because indiv iduals with
very different backgrounds were able to address old problems from
fresh angles. This volume, published in January, 1981, contains the
papers presented dur ing the wor kshop held in June, 1980, in
Noordwijk/Leiden, The Netherlands. In addition, we have in cluded
the extensive discussions, edited by experts in the field, which
followed each presentation. Finally, each main category is followed
by a summary of the topic covered as well as many valuable
conclusions concerning the significance of recent work and ideas
for new directions in research. In the Preface, J.B. Kirsner gives
a comprehensive review of the material, and in an Afterword A.J.Ch.
Haex deals with a num ber of other aspects. We believe that this
volume will be of value to a wide spectrum of scientists and
clinicians and that it will help to establ ish the mul tid
isciplinary approach to Crohn' s dis ease as the one that should
predominate in the future.
This book, the proceedings of Falk Symposium No. 104, organized in
collaboration with the Society of Mucosal Immunology, and held in
Saarbrucken, Germany, March 5-7 1998, is centered around the
immunological mechanisms of mucosal protection and their
disturbances leading to intestinal inflammation and destruction.
This is a rapidly expanding field involving recent knowledge of
basic immunology and cell biology as well as clinical observations.
The conference and this book summarize very recent data in this
field and suggest strategies for future research and clinical
applications, and will be of interest to both basic scientists and
clinicians.
This book, the proceedings of Falk Symposium 133 on Mechanisms of
Intestinal Inflammation: Implications for Therapeutic Intervention
in IBD', held in Berlin, Germany, on 10-11 June 2003, summarizes
present knowledge in the area of unspecific and specific immune
reactions in the gut, recording the gaps in our knowledge and, in
particular, presenting the possibilities of targeted intervention.
The link to inflammatory bowel diseases - Crohn's disease and
ulcerative colitis - is always in focus. Chapters by an
international panel of basic scientists, clinical researchers and
clinicians also record the problems which can originate through
today's possible modulation of the immune reaction, setting the
basis for review of clinical problems. This book is valuable
readings for all scientists and physicians, who, from different
perspectives, have an interest in research on IBD and in the
clinical management of these diseases.
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