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New interventions are needed to reduce the burden of vector-borne diseases like malaria and denguA(c), which are among the most serious and prevalent infectious diseases worldwide. The release of genetically modified (GM) mosquitoes may offer an alternative strategy to do so while circumventing the pitfalls of current vector control methods. Current methodologies are stalling because of drug resistance, absence of vaccines and inadequate mosquito control techniques. GM mosquitoes have been developed that are resistant to pathogen infection and transmission, but the public-health and environmental consequences of releasing such insects are unclear, mainly because of a lack of knowledge of the ecology and population biology of mosquitoes. This book is the reflection of a workshop, held in June 2002, that addressed these issues. Experts on mosquito ecology met for the first time to discuss the current knowledge of mosquito ecology with respect to GM-insect technology. Emphasis of the workshop was on evaluating how human health and natural ecosystems, including target wild-mosquito populations, will respond to the invasion of GM vectors. This volume will stimulate discussion by clearly showing the importance of vector ecology for prevention of vector-borne diseases.
New interventions are needed to reduce the burden of vector-borne
diseases like malaria and denguA(c), which are among the most
serious and prevalent infectious diseases worldwide. The release of
genetically modified (GM) mosquitoes may offer an alternative
strategy to do so while circumventing the pitfalls of current
vector control methods. Current methodologies are stalling because
of drug resistance, absence of vaccines and inadequate mosquito
control techniques. GM mosquitoes have been developed that are
resistant to pathogen infection and transmission, but the
public-health and environmental consequences of releasing such
insects are unclear, mainly because of a lack of knowledge of the
ecology and population biology of mosquitoes.
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