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In this research work, synthesis of Schiff bases was carried by
simple synthetic route. In the first step, the synthesis of
dialdehyde 4, 4'-(propane-1, 3-diylbis (oxy)) dibenzaldehyde was
done through simple reaction, from which three products were
obtained and the desired dialdehyde was isolated by column
chromatography. Using this dialdehyde, a series of
pharmacologically important Schiff bases were synthesized.
Apolipoproteins B/A1 are protein components of antherogenic and non
antherogenicparticles. At the moment, measurement of LDL and HDL in
various combinations is in practice for diagnosis of
atherosclerotic CAD. But studies have proved that measurement of
their protein components is much better, cost effective, error free
and standardize. the current cross sectional analytical study has
confirmed that Apo B/A1 ratio is much better biochemical indicator
and people with obesity, high hip to waist ratio and other known
risk factors for CAD can be better identified for future risk of
CAD by measuring their Apo B/A1 ratio specially in men, however
value 1.8 rather than 0.9 can be more useful. Therefore all old age
men with known risk factor must immediately be monitored and given
lipid lowering drugs for prevention of developing CAD.
The story in this book is about a biologically potent new ligand
monobutylphthalate which has been synthesized by the ring opening
reaction of phthalic anhydride with butanol using dean stalk trap.
Eight transition metal complexes have been synthesized from this
novel ligand in 1:1 and 2:1 stoichiometry. The geometry of the
resulting complexes was proposed through IR spectroscopy. Ligand
and complexes were than subjected to various bacteria and fungi in
order to establish their biological activity. Results reveal that
the ligand and complexes exhibit significant to promising activity
against all type of bacteria and fungi. This monograph is equally
beneficial for both beginners and also ideal for experts
The story in this book is about a series of 1-(2-
methoxyphenyl)-3-pivaloyl thiourea. substituted guanidine which
were synthesized in good yield by condensation reaction of
1-(2-methoxyphenyl)-3- pivaloyl substituted thiourea with different
aromatic amines by using HgCl2 as guanilating agent. These
guanidines have a very high tendency to coordinate with Cu (II).
All the spectroscopic results indicate that guanidines act as
bidentate ligands through oxygen and nitrogen atoms. The products
were characterized by using FT-IR, NMR (1H, 13C) and magnetic
susceptibility techniques. The guanidines and their copper
complexes were also subjected to various microorganisms in order to
establish their bactericidal activity. In short this book is very
much beneficial both for bigginers and for higher research
scholars.
The use of minerals and plant-based medicines are believed to date
back to prehistoric medicine. The first use of drugs to treat
cancer, however, was in the early 20th century, although it was not
originally intended for that purpose. Mustard gas was used as a
chemical warfare agent during World War I and was studied further
during World War II. During a military operation in World War II, a
group of people were accidentally exposed to mustard gas and were
later found to have very low white blood cell counts. This book
explains a detail about the developments of anticancer drugs from
plants to synthetic and from old times to recent. This book is a
collection of various reviews which helps readers of all ares to
understand
Metal Complexes, especially Transition metal complexes have
gigantic role in modern Chemistry. This book contains the some
biologically potent transition metal complexes. This book is a
leading and unique for synthetic chemists explaining the route to
synthesize metal complexes and their handling. Biological portion
sufficiently explains the role of metal complexes as bactericidal
agents. All-together this book is equally beneficial both for
beginners and for the synthetic specialists
Mannich bases are very important and constructive compounds in
organic synthesis, especially their role in biochemistry and
natural products is of capital importance. A lot of work is going
on over the synthesis, characterization and investigation of
bioactivity of these compounds. In The present communication some
novel Mannich bases derived from various aromatic aldehydes and
aromatic amines with 2- butanone are reported with their biological
role. The surprising spectra results showed some Schiff base
formation along with the Mannich bases and this eventually
establish a new method for the preparation of Schiff bases through
acid catalyzed reaction first time. The novelty and biological role
of these Mannich and Schiff bases are also reported here in this
communication.
The metal ions with biologically active ligands are a subject of
considerable interest. The present publication allows the reader to
find information about the latest developments in the field of
organotin chemistry, including their geometric and biological
studies. This publication is divided into four chapters, each
chapter will be self explanatory with good background so that it
can be easily understood at all levels. Novel tin based drugs with
sufficient spectral analysis along with their biological role as an
antibacterial, anti-inflammatory, antifungal and anticancer agents
will be discussed in detail.
This Book has primarily been written keeping in view the needs and
interest of students of various universities. It has been divided
in to two main sections. The first section covers the basic of Flow
Injection analysis, different factors effecting on it and their
optimizations, the second section consist on application of this
technique in development of new methods for determination of a well
known pesticide. Some of the salient features of the book amongst
many are that it is simple and lucid presentation, comprehensively
covers the FIA and provides the systematic treatment of topics,
application of this new emerging technique in development of new
methods by using spectrophotometer
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Paperback
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R398
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Discovery Miles 3 300
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