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Lead (Pb) is an environmental pollutant, especially due to its
anthropogenic activity.The present study aimed to investigate some
of the toxic effects of lead exposure in quails and its
amelioration through vitamin E supplementation. A total number of
420, day old chicks of Japanese quail were assigned seven dietary
treatments.. Control group received only basal diet without any
supplementation. Other groups received lead (Pb) alone or in
different combinations with vitamin E. Lead (Pb) was administered
in the feed at a dose level of 50, 75 and 100 mg/kg Pb. Vitamin E
was administered in the feed at a dose level of 40mg/kg vit E .The
body weight of each bird was weighed weekly and found significant
changes in the weight of quails. Pathological lesions in lead (Pb)
fed birds included enlarged, pale, friable liver and swollen
kidneys.On the other hand, supplementation of vitamins E in lead
intoxicated birds showed ameliorative effects in Lead (pb)
toxicity. It was concluded that the vitamin E ameliorated the lead
induced toxic effects in some of parameters studied
This study was carried out on 90 one-day-old broiler chicks to know
clinico-hematological alterations, DNA damage caused by
cypermethrin (CY), and attenuation of toxic effects by vitamin E
(Vit E) and selenium (Se). Birds were randomly divided into five
equal groups.Birds were monitored twice daily for clinical signs.
They were weighed and blood samples were collected for
hematological studies. CY-treated birds showed more prominent signs
of toxicity compared to CY+Vit E, CY+Se and CY+Vit E+Se birds. Body
weight in groups 1-3 was significantly (P>0.05) smaller at days
20 and 30 when compared with the control group. Significantly
(P>0.001) higher numbers of micronuclei appeared in chicks
treated with CY compared to CY+Vit E- and CY+Se-treated birds.
Significantly decreased total erythrocyte counts (TEC), hemoglobin
(Hb) concentration and packed cell volume (PCV) in all treated
groups were recorded.It can be concluded that CY induces toxic
effects in broilers chicks; however, these toxic effects can be
ameliorated by Vit E or Se. Combination of Vit E and Se was more
effective to ameliorate toxic effects of cypermethrin.
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