Lead (Pb) is an environmental pollutant, especially due to its anthropogenic activity.The present study aimed to investigate some of the toxic effects of lead exposure in quails and its amelioration through vitamin E supplementation. A total number of 420, day old chicks of Japanese quail were assigned seven dietary treatments.. Control group received only basal diet without any supplementation. Other groups received lead (Pb) alone or in different combinations with vitamin E. Lead (Pb) was administered in the feed at a dose level of 50, 75 and 100 mg/kg Pb. Vitamin E was administered in the feed at a dose level of 40mg/kg vit E .The body weight of each bird was weighed weekly and found significant changes in the weight of quails. Pathological lesions in lead (Pb) fed birds included enlarged, pale, friable liver and swollen kidneys.On the other hand, supplementation of vitamins E in lead intoxicated birds showed ameliorative effects in Lead (pb) toxicity. It was concluded that the vitamin E ameliorated the lead induced toxic effects in some of parameters studied

This study was carried out on 90 one-day-old broiler chicks to know clinico-hematological alterations, DNA damage caused by cypermethrin (CY), and attenuation of toxic effects by vitamin E (Vit E) and selenium (Se). Birds were randomly divided into five equal groups.Birds were monitored twice daily for clinical signs. They were weighed and blood samples were collected for hematological studies. CY-treated birds showed more prominent signs of toxicity compared to CY+Vit E, CY+Se and CY+Vit E+Se birds. Body weight in groups 1-3 was significantly (P>0.05) smaller at days 20 and 30 when compared with the control group. Significantly (P>0.001) higher numbers of micronuclei appeared in chicks treated with CY compared to CY+Vit E- and CY+Se-treated birds. Significantly decreased total erythrocyte counts (TEC), hemoglobin (Hb) concentration and packed cell volume (PCV) in all treated groups were recorded.It can be concluded that CY induces toxic effects in broilers chicks; however, these toxic effects can be ameliorated by Vit E or Se. Combination of Vit E and Se was more effective to ameliorate toxic effects of cypermethrin.