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Nanotherapeutics in Cancer Vaccination and Challenges consolidates
the current research on cancer nanomedicine and therapeutic cancer
vaccination to explore the most effective and promising avenues.
The book covers cancer vaccines before exploring nanotherapeutics,
DNA and mRNA vaccines in cancer treatment. Finally, it considers
regulatory and industrial perspectives on cancer vaccination and
nanotherapeutics. This resource will be useful for pharmaceutical
scientists and researchers focused on biomedical engineering,
chemical engineering, vaccine development, and cancer
immunotherapy, along with advanced students in these subjects.
Cancer is arguably the most complex and challenging disease known
to mankind. Over the last two-decades, significant advancements
have been made in new and novel concepts of cancer nanomedicines.
Therapeutic cancer vaccines may be utilized to inhibit further
growth of advanced cancers and/or relapsed tumors that are
refractory to conventional therapies, such as surgery, radiation
therapy and chemotherapy.
Handbook of Analytical Quality by Design addresses the steps
involved in analytical method development and validation in an
effort to avoid quality crises in later stages. The AQbD approach
significantly enhances method performance and robustness which are
crucial during inter-laboratory studies and also affect the
analytical lifecycle of the developed method. Sections cover sample
preparation problems and the usefulness of the QbD concept
involving Quality Risk Management (QRM), Design of Experiments
(DoE) and Multivariate (MVT) Statistical Approaches to solve by
optimizing the developed method, along with validation for
different techniques like HPLC, UPLC, UFLC, LC-MS and
electrophoresis. This will be an ideal resource for graduate
students and professionals working in the pharmaceutical industry,
analytical chemistry, regulatory agencies, and those in related
academic fields.
The nanotheranostics sector provides a very promising strategy for
monitoring drug biodistribution and pathology longitudinal
processes by integrating the imaging and drug delivery functions in
one single nanoformulation, providing vital insights into the
identification of tumour and predicting the efficacy of
nanomedicine. For its unique properties, which include their small
size and biocompatibility and ability to permeate the cellular
membrane with carrying drugs, nanomaterials have been used for
various biomedical applications. This book coversĀ the
progress made in hormone-related cancer and their management by
nonmedicinal therapy for targeting the hormone regulated cancer
with their clinical progress and clinical hurdles.
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