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Applied Multivariate Analysis in Structure Activity Relationships and Environmental Studies - Eurocourse Lectures (Hardcover):... Applied Multivariate Analysis in Structure Activity Relationships and Environmental Studies - Eurocourse Lectures (Hardcover)
James Devillers, Walter Karcher
R2,996 Discovery Miles 29 960 Ships in 18 - 22 working days

Presentation of correspondence analysis and multiple correspondence analysis with the help of examples..- Multiple factor analysis: a method to analyse several groups of variables measured on the same set of individuals..- Principal component and correspondence analyses with respect to instrumental variables: an overview of their role in studies of structure-activity and species-environment relationships..- Basic procedures in hierarchical cluster analysis..- Interpretation of hierarchical clustering..- Graphical techniques for multidimensional data analysis..- Factor analysis and risk perception..- The use of similarity and clustering techniques for the prediction of molecular properties..- Multivariate analysis of the input and output data in the fugacity model level I..- Multivariate analyses in genetic toxicology..- A structure-biodegradability relationship model by discriminant analysis..- Multivariate image analysis in chemistry: an overview..- Chemical multivariate image analysis: some case studies..- Multilayer neural networks applied to structure-activity relationships..

Dibenzanthracenes and Environmental Carcinogenesis (Paperback): Walter Karcher Dibenzanthracenes and Environmental Carcinogenesis (Paperback)
Walter Karcher
R1,180 Discovery Miles 11 800 Ships in 10 - 15 working days

First published in 1992, this volume provides a systematic survey of the dibenzanthracenes and of their chemical, physiochemical and biological properties. The carcinogenic potential of the dibenzanthracenes - an important subclass of polycyclic aromatic hydrocarbons - has been extensively studied and documented since their identification as animal skin carcinogens was first demonstrated in the 1930s. the volume treats the nomenclature, the chemical and physical properties and the synthesis and preparation of the five principal isomers of the dibenzanthracenes series: dibenz (a, h), - dibenz (a, c), -dibenz (aj) anthracene, benzo(a)naphthacene and pentacene. Other chapters are devoted to their occurrence and analysis in the environment, in industrial processes and effluents, and in foodstuffs. The second part addresses their biological activity and reviews the metabolism, cellular interactions, toxicology mutagenicity and carcinogenicity of the dibenzanthracenes. The final chapter is devoted to structure-activity relationships in this class of aromatic compounds. This is the first comprehensive account of this important group of environmental pollutants and carcinogens. It will be of interest to all scientists studying carcinogenesis, and the mutagenicity and toxicology of environmental pollutants.

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