Frontiers in Biochip Technology
Dr. Wan-Li Xing and Dr. Jing Cheng

Frontiers in Biochip Technology serves as an essential collection of new research in the field of biochip technology. This comprehensive collection covers emerging technologies and cutting a "edge research in the field of biochip technology, with all chapters written by the international stars of this evolving field.

Key topics and current trends in biochip technology covered include:

-microarray technology and its applications

- microfluidics

- drug discovery

- detection technology

- lab-on-chip technology and bioinformatics.

Frontiers in Biochip Technology is an important volume for all biotechnologists, bioengineers, genetic engineers, pharmacological researchers, and general bench researchers who want to be up-to-date on the latest advances in the rapidly growing field of biochip technology.

The Editors:

Dr. Wan-Li Xing, Tsinghua University School of Medicine, National Engineering Research Center for Beijing Biochip Technology (NERCBBT), and CapitalBio Corporation, Beijing, China
Dr. Xing is a Professor at Medical Systems Biology Research Center, Tsinghua University School of Medicine, and also serves as the Executive Deputy Director at NERCBBT, CapitalBio Corporation, a world-leader in biochip research. Dr. Xing has published widely and obtained many patents and applications.

Dr. Jing Cheng, Tsinghua University School of Medicine, National Engineering Research Center for Beijing Biochip Technology (NERCBBT), and CapitalBio Corporation, Beijing, China
Dr. Jing Cheng is the Cheung Kong Professor at Medical Systems Biology Research Center, Tsinghua University School ofMedicine, the Director of NERCBBT and CEO & CTO of CapitalBio. Dr. Cheng developed the worlda (TM)s first system of laboratory-on-a-chip in 1998; this work was featured in the front-cover story of the June 1998 issue of Nature Biotechnology and cited as the breakthrough of the year by Science in the same year. He has been awarded Nanogena (TM)s most prestigious award Nano Grant, Distinguished Achievement Award for Overseas Chinese Scholars Returned, Chinaa (TM)s Science & Technology Award for Outstanding Youth, and Qiushi Technology Transfer Award for Outstanding Youth. Dr. Cheng has published over 90 peer-reviewed papers. In addition, he has obtained over 60 European and U.S. patents and applications.

This book brings together contributions from internationally renowned experts in the biochip field. These chapters present not only the authors' latest research work, but also discuss current trends in biochip technology. Specific topics include microarray technology and its applications, microfluidics, drug discovery, detection technology, lab-on-chip technology and bioinformatics. Both newcomers to the field and experienced biochip researchers will benefit from this book.

In the past few years, the application of proteomics to examine the molecular mechanisms underlying (mal-)functioning of the nervous system and brain disorders has risen steeply, which in many cases has yielded novel insights. As neuroproteomics is a new research field involving the use of a number of high-end analytical instruments and technologies, both promises and pitfalls may not be well appreciated by the researchers, and the design of a proper proteomics experiment may not be obvious. "Neuroproteomics" brings together a collection of detailed protocols written by experienced professionals in the field in order to cover aspects of various dimensions of this new technology, together with some established methods that have supporting roles in the workflow of neuroproteomics. Written for the popular "Neuromethods" series, the chapters in this book contain step-by-step, easy to follow instruction along with practical tips and key implementation advice essential for successful implementation of the techniques.

Authoritative and cutting-edge, "Neuroproteomics" will be of great assistance to all researchers seeking to design and execute their own proteomics experiments in an optimal way and continue moving forward this exciting area of study.

Yang Wan-Li (11271206) is one of China's four masters of Southern Sung poetry. These poems were written at what could be seen as a low point in Sung history: an invasion by the Jurchens had forced the Sung to flee to the southern city of Hangchow. But they created at Hangchow a refuge of elegant solitude from which they gazed longingly toward the north, and in this quiet setting, they were able to enjoy the beauties of nature. Many of the poems are perfect verbalizations of the magnificent landscape paintings of the Sung painters: misty, ethereal and luminous. The poetry, however, also holds the annoyances of overwork, aching feet, creaking bones and the pleasures of wine, filling it with humanity and a zest for living.

This book brings together contributions from internationally renowned experts in the biochip field. The authors present not only their latest research work, but also discuss current trends in biochip technology. Specific topics range from microarray technology and its applications to lab-on-a-chip technology.

Frontiers in Biochip Technology
Dr. Wan-Li Xing and Dr. Jing Cheng

Frontiers in Biochip Technology serves as an essential collection of new research in the field of biochip technology. This comprehensive collection covers emerging technologies and cutting -edge research in the field of biochip technology, with all chapters written by the international stars of this evolving field.

Key topics and current trends in biochip technology covered include:

-microarray technology and its applications

- microfluidics

- drug discovery

- detection technology

- lab-on-chip technology and bioinformatics.

Frontiers in Biochip Technology is an important volume for all biotechnologists, bioengineers, genetic engineers, pharmacological researchers, and general bench researchers who want to be up-to-date on the latest advances in the rapidly growing field of biochip technology.

The Editors:

Dr. Wan-Li Xing, Tsinghua University School of Medicine, National Engineering Research Center for Beijing Biochip Technology (NERCBBT), and CapitalBio Corporation, Beijing, China
Dr. Xing is a Professor at Medical Systems Biology Research Center, Tsinghua University School of Medicine, and also serves as the Executive Deputy Director at NERCBBT, CapitalBio Corporation, a world-leader in biochip research. Dr. Xing has published widely and obtained many patents and applications.

Dr. Jing Cheng, Tsinghua University School of Medicine, National Engineering Research Center for Beijing Biochip Technology (NERCBBT), and CapitalBio Corporation, Beijing, China
Dr. Jing Cheng is the Cheung Kong Professor at Medical Systems Biology Research Center, Tsinghua University School of Medicine, the Director of NERCBBT and CEO & CTO of CapitalBio. Dr. Cheng developed the world's first system of laboratory-on-a-chip in 1998; this work was featured in the front-cover story of the June 1998 issue of Nature Biotechnology and cited as the breakthrough of the year by Science in the same year. He has been awarded Nanogen's most prestigious award Nano Grant, Distinguished Achievement Award for Overseas Chinese Scholars Returned, China's Science & Technology Award for Outstanding Youth, and Qiushi Technology Transfer Award for Outstanding Youth. Dr. Cheng has published over 90 peer-reviewed papers. In addition, he has obtained over 60 European and U.S. patents and applications.

This book presents a detailed pedagogical description of the 5G commercial wireless communication system design, from an end to end perspective. It compares and contrasts NR with LTE, and gives a concise and highly accessible description of the key technologies in the 5G physical layer, radio access network layer protocols and procedures. This book also illustrates how the 5G core and EPC is integrated into the radio access network, how virtualization and edge computer fundamentally change the way users interact with the network, as well as 5G spectrum issues. This book is structured into six chapters. The first chapter reviews the use cases, requirements, and standardization organization and activities for 5G. These are 5G requirements and not NR specifically, as technology that meets the requirements, may be submitted to the ITU as 5G technology. This includes a set of Radio Access Technologies (RATs), consisting of NR and LTE; with each RAT meeting different aspects of the requirements. The second chapter describes the air interface of NR and LTE side by side. The basic aspects of LTE that NR builds upon are first described, followed by sections on the NR specific technologies, such as carrier/channel, spectrum/duplexing (including SUL), LTE/NR co-existence and new physical layer technologies (including waveform, Polar/LDPC codes, MIMO, and URLLC/mMTC). In all cases the enhancements made relative to LTE are made apparent. The third chapter contains descriptions of NR procedures (IAM/Beam Management/Power control/HARQ), protocols (CP/UP/mobility, including grant-free), and RAN architecture. The fourth chapter includes a detailed discussion related to end-to-end system architecture, and the 5G Core (5GC), network slicing, service continuity, relation to EPC, network virtualization, and edge computing. The fifth and major chapter describes the ITU submission and how NR and LTE meet the 5G requirements in significant detail, from the rapporteur responsible for leading the preparation and evaluation, as well as some field trial results. Engineers, computer scientists and professionals with a passing knowledge of 4G LTE and a comprehensive understanding of the end to end 5G commercial wireless system will find this book to be a valuable asset. Advanced-level students and researchers studying and working in communication engineering, who want to gain an understanding of the 5G system (as well as methodologies to evaluate features and technologies intended to supplement 5G) will also find this book to be a valuable resource.

In the past few years, the application of proteomics to examine the molecular mechanisms underlying (mal-)functioning of the nervous system and brain disorders has risen steeply, which in many cases has yielded novel insights. As neuroproteomics is a new research field involving the use of a number of high-end analytical instruments and technologies, both promises and pitfalls may not be well appreciated by the researchers, and the design of a proper proteomics experiment may not be obvious. Neuroproteomics brings together a collection of detailed protocols written by experienced professionals in the field in order to cover aspects of various dimensions of this new technology, together with some established methods that have supporting roles in the workflow of neuroproteomics. Written for the popular Neuromethods series, the chapters in this book contain step-by-step, easy to follow instruction along with practical tips and key implementation advice essential for successful implementation of the techniques. Authoritative and cutting-edge, Neuroproteomics will be of great assistance to all researchers seeking to design and execute their own proteomics experiments in an optimal way and continue moving forward this exciting area of study.

Discusses ecofeminism in the context of the social, political and ecological consequences of globalization. The book includes case studies, essays, theoretical works, and articles on ecofeminist movements from many of the world's regions including Taiwan, Mexico, Kenya, Chile, India, Brazil, Canada, England and the United States.