As Louise Brown -- the first baby conceived by in vitro fertilization -- celebrates her 30th birthday, Margaret Marsh and Wanda Ronner tell the fascinating story of the man who first showed that human in vitro fertilization was possible.

John Rock spent his career studying human reproduction. The first researcher to fertilize a human egg in vitro in the 1940s, he became the nation's leading figure in the treatment of infertility, his clinic serving rich and poor alike. In the 1950s he joined forces with Gregory Pincus to develop oral contraceptives and in the 1960s enjoyed international celebrity for his promotion of the pill and his campaign to persuade the Catholic Church to accept it.

Rock became a more controversial figure by the 1970s, as conservative Christians argued that his embryo studies were immoral and feminist activists contended that he had taken advantage of the clinic patients who had participated in these studies as research subjects.

Marsh and Ronner's nuanced account sheds light on the man behind the brilliant career. They tell the story of a directionless young man, a saloon keeper's son, who began his working life as a timekeeper on a Guatemalan banana plantation and later became one of the most recognized figures of the twentieth century. They portray his medical practice from the perspective of his patients, who ranged from the wives of laborers to Hollywood film stars.

The first scholars to have access to Rock's personal papers, Marsh and Ronner offer a compelling look at a man whose work defined the reproductive revolution, with its dual developments in contraception and technologically assisted conception.

"Selected by" Choice" magazine as an Outstanding Academic Title for 1996""[Marsh and Ronner make for] a highly successful combination in which faultless clinical detail and a broad social and cultural approach are seamlessly woven to produce a very impressive and beautifully written historical work of the first importance." -- Irvine Louden, "Journal of the Social History of Medicine"

In "The Empty Cradle," Margaret Marsh and Wanda Ronner delve into the origins of the many misconceptions surrounding infertility as they explore how medical and cultural beliefs emerged throughout its controversial history. Drawing on a wide variety of sources -- including intimate diaries and letters, patient records, memoirs, medical literature, and popular magazines -- "The Empty Cradle" investigates the social, cultural, scientific, and medical dimensions of infertility over the past three hundred years.

Marsh and Ronner explore reactions -- among both physicians and husbands -- to the emerging scientific evidence that infertility was a condition for which men and women bear equal responsibility. The book concludes that infertility is still a subject affected by myth and misunderstanding. A lively and compelling history of a complex medical and cultural phenomenon, "The Empty Cradle" brings a valuable perspective to current debates about how we should think about and address the experience of infertility in our own time.

"Marsh and Ronner have sought to go beyond the published medical literature to disclose the voices of those most affected by the physiological and cultural condition of infertility... they have restored to the historical record the anguish and the hopes of women whoexperienced infertility." -- Rima D. Apple, "American Historical Review"

"The book's lucid explanations of medical terms and procedures will allow me to recommend it to my infertility patients. I plan to do so, trusting that it will give them a new perspective on their predicament. Knowing that it provided me a new perspective on both infertility and the practice of gynecology, I will also assign it an honored place in my medical library." -- Janet E. Shepherd, M.D., "Journal of the American Medical Association"

" "The Empty Cradle" demonstrates the profound impact of politics as well as culture on the development of medical practice. It is an excellent model for future scholarship on the complex relationship between science and society." -- Elaine Tyler May, "Journal of the History of Medicine and Allied Sciences"