This book investigates in detail the concepts and principles of green chemistry and related methodologies, including green synthesis, green activation methods, green catalysis, green solvents, and green design to achieve process intensification while at the same time ensuring process safety and promoting ecological civilization and environmental protection. Moreover, it incorporates elements of chemical management and chemical education, highlighting chemists' responsibility to protect humankind and foster green and sustainable development in chemistry. Combining Chinese and Belarus wisdom, this book is intended for those working in the chemical industry who are interested in environmental protection and sustainable development, as well as undergraduate and graduate students who are interested in green chemistry and related technologies.

This authoritative volume provides a holistic picture of antibody-drug conjugates (ADCs). Fourteen comprehensive chapters are divided into six sections including an introduction to ADCs, the ADC construct, development issues, landscape, IP and pharmacoeconomics, case studies, and the future of the field. The book examines everything from the selection of the antibody, the drug, and the linker to a discussion of developmental issues such as formulations, bio-analysis, pharmacokinetic-pharmacodynamic relationships, and toxicological and regulatory challenges. It also explores pharmacoecomonics and intellectual properties, including recently issued patents and the cost analysis of drug therapy. Case studies are presented for the three ADCs that have received FDA approval: gemtuzumab ozogamicin (Mylotarg (R)), Brentuximab vedotin (Adcetris (R)), and ado-trastuzumab emtansine (Kadcyla (R)), as well as an ADC in late-stage clinical trials, glembatumumab vedotin (CDX-011). Finally, the volume presents a perspective by the editors on the future directions of ADC development and clinical applications. Antibody-Drug Conjugates is a practical and systematic resource for scientists, professors, and students interested in expanding their knowledge of cutting-edge research in this exciting field.

This guidebook on e-science presents real-world examples of practices and applications, demonstrating how a range of computational technologies and tools can be employed to build essential infrastructures supporting next-generation scientific research. Each chapter provides introductory material on core concepts and principles, as well as descriptions and discussions of relevant e-science methodologies, architectures, tools, systems, services and frameworks. Features: includes contributions from an international selection of preeminent e-science experts and practitioners; discusses use of mainstream grid computing and peer-to-peer grid technology for "open" research and resource sharing in scientific research; presents varied methods for data management in data-intensive research; investigates issues of e-infrastructure interoperability, security, trust and privacy for collaborative research; examines workflow technology for the automation of scientific processes; describes applications of e-science.

The book is a translation of the second edition of a much-used and research-based Chinese textbook. As a succinct and issue-based introduction to the Western philosophy of science, the book brings eight focal issues in the field to the fore and augments each topic by incorporating Chinese perspectives. Followed by an overview of the historical framework and logical underpinnings of the philosophy of science, the book thoroughly discusses eight issues in the discipline: (1) the criteria of cognitive meaning, (2) induction and confirmation, (3) scientific explanation, (4) theories of scientific growth, (5) the demarcation between science and pseudoscience, (6) scientific realism and empiricism; (7) the philosophy of scientific experimentation, (8) science and value. Not confined to Western mainstream discourse in this field, the book also introduces voices of Chinese philosophers of note and adopts a stance that productively combines logical empiricism and Kuhnianism, both of which tend to be covered in less detail by many English language textbooks. In the final chapter the author offers a prognosis regarding the future of the discipline based on recent trends. This book will be of value to students who study philosophy of science and hope to gain a better understanding of science and technology.

This book provides a comprehensive overview on the recent significant advancements of conductive polymers and their composites in terms of conductive mechanism, fabrication strategies, important properties, and various promising applications. The corresponding knowledge was systematically compiled in the logical order and demonstrated as seven chapters. The special structure, influencing factors of the conductivity, the charge carrier transport model, the wettability and classical categories of the conductive polymers are narrated. Both conventional and novel strategies undertaken to fabricate the conductive polymers are introduced, as provided the overall master of the progress. In comparison with the bulk counterpart, nanostructured conductive polymers with different dimensions such as nanospheres, nano-networks, nanotubes and nanowire arrays are produced through distinct methods, thus presenting unique and distinct performance endowed by the nanometer scale. The combination of conductive polymers with other functional materials results in a number of the composites with improved properties by synergistic effect. The superior performance of conductive polymers and their composites greatly facilitates their development toward various important applications in the advanced and sophisticated fields such as biological utilization, energy storage and sensors. Due to their excellent biocompatibility, conductive polymers and their composites stand out to be useful in the biological field including tissue engineering, drug delivery and artificial muscle. To meet the urgent demand of the energy storage, conductive polymers and their composites play an important role in the devices including supercapacitors, solar cells and fuel cells. Finally, development of conductive polymers and their composites in the modern industry is greatly enhanced by their applications in smart sensors such as conductometric sensors, gravimetric sensors, optical sensors, chemical sensors and biosensors. This book has significant value for researchers, graduate students, and engineers carrying out the fundamental research or industrial production of conductive polymers and their composites.

This book focuses on how to promote cross-border economic cooperation in the context of China national strategy including BRI. This book summarizes the existing regional economic development theories and sorts out the relevant theories of cross-border economic cooperation. Then, it analyzes the industrial development of China's southwestern border and neighboring countries, the main reasons of rural household poverty in the border ethnic areas by means of empirical methods, and proposes corresponding policy implications. Also, it explores the current border investment and trade policies of China, and compares the similarities and differences between China and Vietnam, and Laos and Myanmar.

The relation between China and Japan is one of the most important bilateral relationships in the world but how did the Japanese view China in ancient times? How did views change throughout the course of history? How could China's image be improved in Japanese people's eyes? This book provides an analysis of the history of contact between China and Japan and surveys the present situation to understand general views of Japanese society toward China. Through scientific public opinion surveys as well as in-depth interviews, the book examines ordinary and elite Japanese people's views of Chinese culture, society, politics, the economy, media and Sino-Japanese relations. In addition, it analyzes the main causes of the formation of such views, and makes suggestions on promoting positive public opinions of China. The authors hope that this title can deepen Japanese society's understanding and comprehension of China, help promote Sino-Japanese non-governmental exchange, and lay the foundation for continuous development of Sino-Japanese relations. This title will appeal to students and scholars of cultural studies, international relations and Asian studies.

The relation between China and Japan is one of the most important bilateral relationships in the world but how did the Japanese view China in ancient times? How did views change throughout the course of history? How could China's image be improved in Japanese people's eyes? This book provides an analysis of the history of contact between China and Japan and surveys the present situation to understand general views of Japanese society toward China. Through scientific public opinion surveys as well as in-depth interviews, the book examines ordinary and elite Japanese people's views of Chinese culture, society, politics, the economy, media and Sino-Japanese relations. In addition, it analyzes the main causes of the formation of such views, and makes suggestions on promoting positive public opinions of China. The authors hope that this title can deepen Japanese society's understanding and comprehension of China, help promote Sino-Japanese non-governmental exchange, and lay the foundation for continuous development of Sino-Japanese relations. This title will appeal to students and scholars of cultural studies, international relations and Asian studies.

Nonlinear Stochastic Control and Filtering with Engineering-oriented Complexities presents a series of control and filtering approaches for stochastic systems with traditional and emerging engineering-oriented complexities. The book begins with an overview of the relevant background, motivation, and research problems, and then: Discusses the robust stability and stabilization problems for a class of stochastic time-delay interval systems with nonlinear disturbances Investigates the robust stabilization and H control problems for a class of stochastic time-delay uncertain systems with Markovian switching and nonlinear disturbances Explores the H state estimator and H output feedback controller design issues for stochastic time-delay systems with nonlinear disturbances, sensor nonlinearities, and Markovian jumping parameters Analyzes the H performance for a general class of nonlinear stochastic systems with time delays, where the addressed systems are described by general stochastic functional differential equations Studies the filtering problem for a class of discrete-time stochastic nonlinear time-delay systems with missing measurement and stochastic disturbances Uses gain-scheduling techniques to tackle the probability-dependent control and filtering problems for time-varying nonlinear systems with incomplete information Evaluates the filtering problem for a class of discrete-time stochastic nonlinear networked control systems with multiple random communication delays and random packet losses Examines the filtering problem for a class of nonlinear genetic regulatory networks with state-dependent stochastic disturbances and state delays Considers the H state estimation problem for a class of discrete-time complex networks with probabilistic missing measurements and randomly occurring coupling delays Addresses the H synchronization control problem for a class of dynamical networks with randomly varying nonlinearities Nonlinear Stochastic Control and Filtering with Engineering-oriented Complexities describes novel methodologies that can be applied extensively in lab simulations, field experiments, and real-world engineering practices. Thus, this text provides a valuable reference for researchers and professionals in the signal processing and control engineering communities.

Identifies Recent Technological Developments Worldwide The field of grid computing has made rapid progress in the past few years, evolving and developing in almost all areas, including concepts, philosophy, methodology, and usages. Grid Computing: Infrastructure, Service, and Applications reflects the recent advances in this field, covering the research aspects that involve infrastructure, middleware, architecture, services, and applications. Grid Systems Across the Globe The first section of the book focuses on infrastructure and middleware and presents several national and international grid systems. The text highlights China Research and Development environment Over Wide-area Network (CROWN), several ongoing cyberinfrastructure efforts in New York State, and Enabling Grids for E-sciencE (EGEE), which is co-funded by the European Commission and the world's largest multidisciplinary grid infrastructure today. The second part of the book discusses recent grid service advances. The authors examine the UK National Grid Service (NGS), the concept of resource allocation in a grid environment, OMIIBPEL, and the possibility of treating scientific workflow issues using techniques from the data stream community. The book describes an SLA model, reviews portal and workflow technologies, presents an overview of PKIs and their limitations, and introduces PIndex, a peer-to-peer model for grid information services. New Projects and Initiatives The third section includes an analysis of innovative grid applications. Topics covered include the WISDOM initiative, incorporating flow-level networking models into grid simulators, system-level virtualization, grid usage in the high-energy physics environment in the LHC project, and the Service Oriented HLA RTI (SOHR) framework. With a comprehensive summary of past advances, this text is a window into the future of this nascent technology, forging a path for the next generation of cyberinfrastructure developers.

Nonlinear Stochastic Control and Filtering with Engineering-oriented Complexities presents a series of control and filtering approaches for stochastic systems with traditional and emerging engineering-oriented complexities. The book begins with an overview of the relevant background, motivation, and research problems, and then: Discusses the robust stability and stabilization problems for a class of stochastic time-delay interval systems with nonlinear disturbances Investigates the robust stabilization and H control problems for a class of stochastic time-delay uncertain systems with Markovian switching and nonlinear disturbances Explores the H state estimator and H output feedback controller design issues for stochastic time-delay systems with nonlinear disturbances, sensor nonlinearities, and Markovian jumping parameters Analyzes the H performance for a general class of nonlinear stochastic systems with time delays, where the addressed systems are described by general stochastic functional differential equations Studies the filtering problem for a class of discrete-time stochastic nonlinear time-delay systems with missing measurement and stochastic disturbances Uses gain-scheduling techniques to tackle the probability-dependent control and filtering problems for time-varying nonlinear systems with incomplete information Evaluates the filtering problem for a class of discrete-time stochastic nonlinear networked control systems with multiple random communication delays and random packet losses Examines the filtering problem for a class of nonlinear genetic regulatory networks with state-dependent stochastic disturbances and state delays Considers the H state estimation problem for a class of discrete-time complex networks with probabilistic missing measurements and randomly occurring coupling delays Addresses the H synchronization control problem for a class of dynamical networks with randomly varying nonlinearities Nonlinear Stochastic Control and Filtering with Engineering-oriented Complexities describes novel methodologies that can be applied extensively in lab simulations, field experiments, and real-world engineering practices. Thus, this text provides a valuable reference for researchers and professionals in the signal processing and control engineering communities.

Separation and characterization of materials is an essential step in the advancement of science and technology. The need for separation and characterization could arise from wishes to obtain purified samples with less contaminants, requirements for quality control of materials for downstream applications, or needs to identify structures and conformations of active species present in the applications. The types of materials encountered in applications are diverse, from synthetic polymers and biological derived biopolymers to micro or submicro particles and various conjugated or self-assembled nanomaterials. This makes the task of separation and characterization challenging. There is no one-size-fits-all approach. Scientists, whether working in academia or in industries, are constantly facing new challenges. Communication between scientists is essential for keeping each other updated on developments in the field. This was the motivation for organizing the symposium on "Recent Progress in Separation of Macromolecules and Particulates" at the 2017 Spring National American Chemical Society (ACS) Meeting in San Francisco. Symposiums based on such a theme have been organized several times in ACS meetings as well as in other settings, but no such symposium books have been published. Hence, the editors decided to put together this symposium book, based on the talks presented at the symposium, in the hope that knowledge shared at the meeting can be shared more broadly within the community and beyond.

This book investigates in detail the concepts and principles of green chemistry and related methodologies, including green synthesis, green activation methods, green catalysis, green solvents, and green design to achieve process intensification while at the same time ensuring process safety and promoting ecological civilization and environmental protection. Moreover, it incorporates elements of chemical management and chemical education, highlighting chemists' responsibility to protect humankind and foster green and sustainable development in chemistry. Combining Chinese and Belarus wisdom, this book is intended for those working in the chemical industry who are interested in environmental protection and sustainable development, as well as undergraduate and graduate students who are interested in green chemistry and related technologies.

Advances in Ultra-low Emission Control Technologies for Coal-Fired Power Plants discusses the emissions standards of dust, SO2, NOx and mercury pollution, also presenting the key technologies available to control emissions in coal-fired power plants. The practical effects of ultra-low emissions projects included help the reader understand related implications in plants. Emphasis is placed on 300MW subcritical, 600MW subcritical, 660MW supercritical and 1000MW ultra-supercritical coal-fired units. The influence of different pollutant control units, such as wet electrostatic precipitator, desulfurization equipment and the electrostatic precipitator are also analyzed, and the pollutant levels before and after retrofitted ultra-low emissions are compared throughout.

This book constitutes the refereed proceedings of the 7th International Conference on Health Information Science, HIS 2018, held in Cairns, QLD, Australia, in October 2018. The 13 full papers and 5 short papers presented were carefully reviewed and selected from 43 submissions. The papers feature multidisciplinary research results in health information science and systems that support health information management and health service delivery. They relate to all aspects of the conference scope, such as medical/health/biomedicine information resources such as patient medical records, devices and equipments, software and tools to capture, store, retrieve, process, analyze, and optimize the use of information in the health domain; data management, data mining, and knowledge discovery, management of public health, examination of standards, privacy and security issues; computer visualization and artificial intelligence for computer aided diagnosis; development of new architectures and applications for health information systems.

This two volume set (CCIS 901 and 902) constitutes the refereed proceedings of the 4th International Conference of Pioneering Computer Scientists, Engineers and Educators, ICPCSEE 2018 (originally ICYCSEE) held in Zhengzhou, China, in September 2018. The 125 revised full papers presented in these two volumes were carefully reviewed and selected from 1057 submissions. The papers cover a wide range of topics related to basic theory and techniques for data science including mathematical issues in data science, computational theory for data science, big data management and applications, data quality and data preparation, evaluation and measurement in data science, data visualization, big data mining and knowledge management, infrastructure for data science, machine learning for data science, data security and privacy, applications of data science, case study of data science, multimedia data management and analysis, data-driven scientific research, data-driven bioinformatics, data-driven healthcare, data-driven management, data-driven eGovernment, data-driven smart city/planet, data marketing and economics, social media and recommendation systems, data-driven security, data-driven business model innovation, social and/or organizational impacts of data science.

This authoritative volume provides a holistic picture of antibody-drug conjugates (ADCs). Fourteen comprehensive chapters are divided into six sections including an introduction to ADCs, the ADC construct, development issues, landscape, IP and pharmacoeconomics, case studies, and the future of the field. The book examines everything from the selection of the antibody, the drug, and the linker to a discussion of developmental issues such as formulations, bio-analysis, pharmacokinetic-pharmacodynamic relationships, and toxicological and regulatory challenges. It also explores pharmacoecomonics and intellectual properties, including recently issued patents and the cost analysis of drug therapy. Case studies are presented for the three ADCs that have received FDA approval: gemtuzumab ozogamicin (Mylotarg®), Brentuximab vedotin (Adcetris®), and ado-trastuzumab emtansine (Kadcyla®), as well as an ADC in late-stage clinical trials, glembatumumab vedotin (CDX-011). Finally, the volume presents a perspective by the editors on the future directions of ADC development and clinical applications. Antibody-Drug Conjugates is a practical and systematic resource for scientists, professors, and students interested in expanding their knowledge of cutting-edge research in this exciting field.

This Springer Brief investigates spectrum sharing with limited channel feedback in various cognitive radio systems, such as point-to-point, broadcast scheduling and ad-hoc networks. The design aim is to optimally allocate the secondary resources to improve the throughput of secondary users while maintaining a certain quality of service for primary users. The analytical results of optimal resource allocation are derived via optimization theory and are verified by the numerical results. The results demonstrate the secondary performance is significantly improved by limited feedback and is further improved by more feedback bits, more secondary receivers and more primary side information.

The book is a translation of the second edition of a much-used and research-based Chinese textbook. As a succinct and issue-based introduction to the Western philosophy of science, the book brings eight focal issues in the field to the fore and augments each topic by incorporating Chinese perspectives. Followed by an overview of the historical framework and logical underpinnings of the philosophy of science, the book thoroughly discusses eight issues in the discipline: (1) the criteria of cognitive meaning, (2) induction and confirmation, (3) scientific explanation, (4) theories of scientific growth, (5) the demarcation between science and pseudoscience, (6) scientific realism and empiricism; (7) the philosophy of scientific experimentation, (8) science and value. Not confined to Western mainstream discourse in this field, the book also introduces voices of Chinese philosophers of note and adopts a stance that productively combines logical empiricism and Kuhnianism, both of which tend to be covered in less detail by many English language textbooks. In the final chapter the author offers a prognosis regarding the future of the discipline based on recent trends. This book will be of value to students who study philosophy of science and hope to gain a better understanding of science and technology.

Modelling and Control of Dynamic Spatially Distributed Systems: Pharmaceutical Processes provides a balanced approach to help readers to get started quickly in the field of biochemical pharmaceuticals. From a theoretical perspective, dynamic spatially distributed systems are introduced to address their industrial applications. After identifying problems, the book provides readers with modeling and control system design techniques via a novel fuzzy set (class of objects with a continuum of grades of membership, to describe the grade of the object belonging to this fuzzy set) and intelligent computation methods. From an application perspective, the book provides a thorough understanding of Good Manufacture Practices (GMP) and the importance of identification, modelling, and intelligent control of such systems, reducing the test-and-error cost, and the R&D design time cycle of original drug development.

This book focuses on how to promote cross-border economic cooperation in the context of China national strategy including BRI. This book summarizes the existing regional economic development theories and sorts out the relevant theories of cross-border economic cooperation.  Then, it analyzes the industrial development of China's southwestern border and neighboring countries, the main reasons of rural household poverty in the border ethnic areas by means of empirical methods, and proposes corresponding policy implications. Also, it explores the current border investment and trade policies of China, and compares the similarities and differences between China and Vietnam, and Laos and Myanmar. 

The two-volume set LNICST 460 and 461 constitutes the proceedings of the 18th EAI International Conference on Collaborative Computing: Networking, Applications and Worksharing, CollaborateCom 2022, held in Hangzhou, China, in October 2022. The 57 full papers presented in the proceedings were carefully reviewed and selected from 171 submissions. The papers are organized in the following topical sections: Recommendation System; Federated Learning and application; Edge Computing and Collaborative working; Blockchain applications; Security and Privacy Protection; Deep Learning and application; Collaborative working; Images processing and recognition.

The two-volume set LNICST 460 and 461 constitutes the proceedings of the 18th EAI International Conference on Collaborative Computing: Networking, Applications and Worksharing, CollaborateCom 2022, held in Hangzhou, China, in October 2022. The 57 full papers presented in the proceedings were carefully reviewed and selected from 171 submissions. The papers are organized in the following topical sections: Recommendation System; Federated Learning and application; Edge Computing and Collaborative working; Blockchain applications; Security and Privacy Protection; Deep Learning and application; Collaborative working; Images processing and recognition.

This book constitutes the proceedings of the 18th International Symposium on Applied Reconfigurable Computing, ARC 2022, held as a virtual event, in September 2022. The 13 full papers presented in this volume were reviewed and selected from 16 submissions. The papers cover a broad spectrum of applications of reconfigurable computing, from driving assistance, data and graph processing acceleration, computer security to the societal relevant topic of supporting early diagnosis of Covid infectious conditions.