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Metalloenzymes: From Bench to Bedside offers a thorough overview of
metalloenzymes, spanning biochemical and structural features,
pharmacology, and biotechnological applications. After a brief
overview, international experts in the field discuss a wide range
of magnesium, calcium, zinc, manganese, nickel, iron, copper,
cadmium, molybdenum, and tungsten enzymes, along with catalytic
roles within their active sites. With a uniform approach
throughout, each chapter includes the structure and function of the
enzyme, physiologic and pathologic roles, inhibitors and activators
of the enzyme (and their design), and clinical agents or compounds
applied in medicine and drug discovery. This book enables
scientists across academia and industry to adopt ongoing
metalloenzyme research, and continuous discovery of novel
metalloenzymes, in new life science studies and clinical
applications.
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