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This book offers a conceptual explanation of the interrelationships
that exist between the stages in the progression of initiated
epithelial cells in culture compared with the diverse tissue of
organs and the progression of tumors from different organ sites.
The fate of the modification of adducts is discussed at the
molecular level. The role that modifications in hot spots in
oncogenes and supressor genes play at the molecular level and how
these molecular modifications can lead to an explanation of
molecular control in the formation of tumor phenotypes is also
examined. Researchers in cell biology and toxicology, applied
pharmacology, carcinogenesis, teratogenesis, mutagenesis, and
molecular toxicology will find the book useful, interesting
reading.
This book offers a conceptual explanation of the interrelationships
that exist between the stages in the progression of initiated
epithelial cells in culture compared with the diverse tissue of
organs and the progression of tumors from different organ sites.
The fate of the modification of adducts is discussed at the
molecular level. The role that modifications in hot spots in
oncogenes and supressor genes play at the molecular level and how
these molecular modifications can lead to an explanation of
molecular control in the formation of tumor phenotypes is also
examined. Researchers in cell biology and toxicology, applied
pharmacology, carcinogenesis, teratogenesis, mutagenesis, and
molecular toxicology will find the book useful, interesting
reading.
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