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Resistance to Anti-CD20 Antibodies and Approaches for Their
Reversal presents in-depth content written by international experts
in the study of resistance to anti-CD20 antibodies and approaches
for their reversal. Anti-CD20 antibodies are used to achieve B cell
depletion and are developed to treat B cell proliferative
disorders, including non-Hodgkin’s lymphoma and chronic
lymphocytic leukemia. In the past two decades, anti-CD20 antibodies
have revolutionized the treatment of all B cell malignancies,
however, there are patients that fail to respond to initial therapy
or relapse sooner. This book explores new and existing avenues
surrounding Anti-CD20 antibodies. In recent years, several
next-generation anti-CD20 therapies have been developed but
predicting and reversing resistance is still a challenging task.
These areas are being actively studied as they represent a
potential to improve anti-CD20 therapies and are discussed
thoroughly in the book. It is a valuable resource for researchers,
students and member of the biomedical and medical fields who want
to learn more about resistance to anti-CD20 antibodies and their
reversal.
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