Recent advances in the processing of microstructured and nanostructured materials are finding application in medical diagnosis and treatment. For example, novel building blocks for bottom-up assembly of biomaterials are being designed that will simplify development of nanostructured materials. In addition, functional biomaterials are being developed that exhibit unique interactions with proteins, nucleic acids, and other biological structures. This book brings together a diverse group of materials researchers, medical device manufacturers and clinicians to discuss the use of novel techniques for processing metals, ceramics, polymers, natural materials and composite materials used in diagnosis and treatment of medical conditions. Topics include: processing of biomimetic materials; materials for bio-imaging; functional biomaterials; nanoparticles for medical diagnosis and treatment; novel materials and devices for drug delivery and biosensing; scaffolds for tissue engineering; self-assembled biomaterials; and surface modification of biomaterials.

"Becoming Big League" is the story of Seattle's relationship with major league baseball from the 1962 World's Fair to the completion of the Kingdome in 1976 and beyond. Bill Mullins focuses on the acquisition and loss, after only one year, of the Seattle Pilots and documents their on-the-field exploits in lively play-by-play sections.

The Pilots' underfunded ownership, led by Seattle's Dewey and Max Soriano and William Daley of Cleveland, struggled to make the team a success. They were savvy baseball men, but they made mistakes and wrangled with the city. By the end of the first season, the team was in bankruptcy. The Pilots were sold to a contingent from Milwaukee led by Bud Selig, who moved the franchise to Wisconsin and rechristened the team the Brewers.

"Becoming Big League" describes the character of Seattle in the 1960s and 1970s, explains how the operation of a major league baseball franchise fits into the life of a city, charts Seattle's long history of fraught stadium politics, and examines the business of baseball.

Bill Mullins received his Ph.D. from the University of Washington and is professor emeritus of history at Oklahoma Baptist University. He lives in Federal Way, Washington.

""Becoming Big League" is written with a verve and wit that makes the most of all the engaging and/or exasperating characters involved." -Carl Abbott, Portland State University