Our understanding of how pain in early life differs to that in maturity is continuing to increase and develop, using a combination of approaches from basic science, clinical science, and implementation science. The new edition of the Oxford Textbook of Pediatric Pain brings together an international team of experts to provide an authoritative and comprehensive textbook on all aspects of pain in infants, children, and youth. Divided into nine sections, the textbook analyses pain as a multifactorial problem to give the reader a comprehensive understanding of this challenging subject. Evidence-based chapters look in depth at topics ranging from the long-term effects of pain in children, to complementary therapy in paediatric pain. The text addresses the knowledge-to-practice gap through individual and organizational implementation, and facilitation strategies. Case examples and perspective boxes are provided to aid learning and illustrate the application of knowledge. Written by clinicians, educators, trainees, and researchers, hand selected by the Editors for their practical approach and expertise in specific subject areas, the new edition of the Oxford Textbook of Pediatric Pain is an essential reference text in the assessment and treatment of patients and families in the field of paediatric pain. Purchasers of the print version of the second edition will have free access on Oxford Medicine Online to all the content for the life of the edition.