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Presenting a state-of-the-art overview of theoretical and
computational models that link characteristic biomechanical
phenomena, this book provides guidelines and examples for creating
multiscale models in representative systems and organisms. It
develops the reader's understanding of and intuition for multiscale
phenomena in biomechanics and mechanobiology, and introduces a
mathematical framework and computational techniques paramount to
creating predictive multiscale models. Biomechanics involves the
study of the interactions of physical forces with biological
systems at all scales - including molecular, cellular, tissue and
organ scales. The emerging field of mechanobiology focuses on the
way that cells produce and respond to mechanical forces - bridging
the science of mechanics with the disciplines of genetics and
molecular biology. Linking disparate spatial and temporal scales
using computational techniques is emerging as a key concept in
investigating some of the complex problems underlying these
disciplines. Providing an invaluable field manual for graduate
students and researchers of theoretical and computational modelling
in biology, this book is also intended for readers interested in
biomedical engineering, applied mechanics and mathematical biology.
Presenting a state-of-the-art overview of theoretical and
computational models that link characteristic biomechanical
phenomena, this book provides guidelines and examples for creating
multiscale models in representative systems and organisms. It
develops the reader's understanding of and intuition for multiscale
phenomena in biomechanics and mechanobiology, and introduces a
mathematical framework and computational techniques paramount to
creating predictive multiscale models. Biomechanics involves the
study of the interactions of physical forces with biological
systems at all scales - including molecular, cellular, tissue and
organ scales. The emerging field of mechanobiology focuses on the
way that cells produce and respond to mechanical forces - bridging
the science of mechanics with the disciplines of genetics and
molecular biology. Linking disparate spatial and temporal scales
using computational techniques is emerging as a key concept in
investigating some of the complex problems underlying these
disciplines. Providing an invaluable field manual for graduate
students and researchers of theoretical and computational modelling
in biology, this book is also intended for readers interested in
biomedical engineering, applied mechanics and mathematical biology.
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