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This book serves as a comprehensive, up-to-date reference about
this cutting-edge laser technology and its many new and interesting
developments. Various aspects and trends of Raman fiber lasers are
described in detail by experts in their fields. Raman fiber lasers
have progressed quickly in the past decade, and have emerged as a
versatile laser technology for generating high power light sources
covering a spectral range from visible to mid-infrared. The
technology is already being applied in the fields of
telecommunication, astronomy, cold atom physics, laser
spectroscopy, environmental sensing, and laser medicine. This book
covers various topics relating to Raman fiber laser research,
including power scaling, cladding and diode pumping, cascade Raman
shifting, single frequency operation and power amplification,
mid-infrared laser generation, specialty optical fibers, and random
distributed feedback Raman fiber lasers. The book will appeal to
scientists, students, and technicians seeking to understand the
recent developments and future trends of this promising and
multifaceted technology.
Advanced Statistics in Regulatory Critical Clinical Initiatives is
focused on the critical clinical initiatives introduced by the 21st
Century Cure Act passed by the United States Congress in December
2016. The book covers everything from the outline of the
initiatives to analysis on the effect on biopharmaceutical research
and development. Advanced Statistics in Regulatory Critical
Clinical Initiatives provides innovative ways to resolve common
challenges in statistical research of rare diseases such small
sample sizes and provides guidance for combined use of data. With
analysis from regulatory and scientific perspectives this book is
an ideal companion for researchers in biostatistics, pharmaceutical
development, and policy makers in related fields. Key Features:
Provides better understanding of innovative design and analysis of
each critical clinical initiatives which may be used in regulatory
review/approval of drug development. Makes recommendations to
evaluate submissions accurately and reliably. Proposes innovative
study designs and statistical methods for oncology and/or rare
disease drug development. Provides insight regarding current
regulatory guidance on drug development such as gene therapy and
rare diseases.
This book serves as a comprehensive, up-to-date reference about
this cutting-edge laser technology and its many new and interesting
developments. Various aspects and trends of Raman fiber lasers are
described in detail by experts in their fields. Raman fiber lasers
have progressed quickly in the past decade, and have emerged as a
versatile laser technology for generating high power light sources
covering a spectral range from visible to mid-infrared. The
technology is already being applied in the fields of
telecommunication, astronomy, cold atom physics, laser
spectroscopy, environmental sensing, and laser medicine. This book
covers various topics relating to Raman fiber laser research,
including power scaling, cladding and diode pumping, cascade Raman
shifting, single frequency operation and power amplification,
mid-infrared laser generation, specialty optical fibers, and random
distributed feedback Raman fiber lasers. The book will appeal to
scientists, students, and technicians seeking to understand the
recent developments and future trends of this promising and
multifaceted technology.
Systems and Synthetic Metabolic Engineering provides an overview of
the development of metabolic engineering within medicine that is
fueled by systems and synthetic biology. These newly developed,
successful strategies of metabolic engineering guide the audience
on how to propose and test proper strategies for metabolic
engineering research. In addition to introductory, regulatory and
challenges in the field, the book also covers dynamic control and
autonomous regulation to control cell metabolism, along with
computational modeling and industrial applications. The book is
written by leaders in the field, making it ideal for synthetic
biologists, researchers, students and anyone working in this area.
This book provides a global perspective on the various issues that
the industry has to face as well as to provide some key global
strategies that can help coping with those global challenges, such
as collaboration, strategic value chain planning, and
interdependency analyses. It presents literature reviews, strategic
research orientations, assessment of some current key issues, and
state-of-the-art methodologies.
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Paperback
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R205
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Discovery Miles 1 640
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