This book constitutes the refereed joint proceedings of the International Workshop on Point-of-Care Ultrasound, POCUS 2018, the International Workshop on Bio-Imaging and Visualization for Patient-Customized Simulations, BIVPCS 2017, the International Workshop on Correction of Brainshift with Intra-Operative Ultrasound, CuRIOUS 2018, and the International Workshop on Computational Precision Medicine, CPM 2018, held in conjunction with the 21st International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2018, in Granada, Spain, in September 2018.The 10 full papers presented at POCUS 2018, the 4 full papers presented at BIVPCS 2018, the 8 full papers presented at CuRIOUS 2018, and the 2 full papers presented at CPM 2018 were carefully reviewed and selected. The papers feature research from complementary fields such as ultrasound image systems applications as well as signal and image processing, mechanics, computational vision, mathematics, physics, informatics, computer graphics, bio-medical-practice, psychology and industry. They discuss intra-operative ultrasound-guided brain tumor resection as well as pancreatic cancer survival prediction.

This book constitutes the refereed joint proceedings of the 4th International Workshop on Large-Scale Annotation of Biomedical Data and Expert Label Synthesis, LABELS 2019, the First International Workshop on Hardware Aware Learning for Medical Imaging and Computer Assisted Intervention, HAL-MICCAI 2019, and the Second International Workshop on Correction of Brainshift with Intra-Operative Ultrasound, CuRIOUS 2019, held in conjunction with the 22nd International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2019, in Shenzhen, China, in October 2019. The 8 papers presented at LABELS 2019, the 5 papers presented at HAL-MICCAI 2019, and the 3 papers presented at CuRIOUS 2019 were carefully reviewed and selected from numerous submissions. The LABELS papers present a variety of approaches for dealing with a limited number of labels, from semi-supervised learning to crowdsourcing. The HAL-MICCAI papers cover a wide set of hardware applications in medical problems, including medical image segmentation, electron tomography, pneumonia detection, etc. The CuRIOUS papers provide a snapshot of the current progress in the field through extended discussions and provide researchers an opportunity to characterize their image registration methods on newly released standardized datasets of iUS-guided brain tumor resection.