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The sparks from the spirit of science include not only new
knowledge but also innovations, the major ingredients of
development and sustainability. This book creates an understanding
of science and its role in innovation and sustainable development
and points out unfilled gaps in human development. It highlights
opportunities for societies to overcome obstacles in development.
The book is written in an easy-to-understand manner, avoiding
technical jargon, and contains case studies, practical examples,
and historical perspectives. It is intended for a general,
especially young readership and will appeal to those curious about
the nature of science and its benefits, together with its possible
pitfalls.
This book is for readers with some background in science,
concerning the search for drugs, starting from molecular diversity
in nature or molecular wilderness. Drug molecules may be used as
such, or as starting points for improved drugs obtained from the
interface of chemistry and biology. In some cases, the essential
molecular features for drug properties from natural molecules may
be identified and modified to more effective ones. In other cases,
nature provides the targets, such as essential enzymes from
infectious microorganisms, from which synthetic drugs can be
designed. The mechanisms of action of drugs can be discerned by
studying target-drug interactions. Nature may fight back, as in
cases when microorganisms become resistant to drugs, but we can
again use the chemistry-biology interface to obtain drugs which
overcome the resistance. The battle goes on, hopefully with victory
for both humans and balance of nature. This book differs from those
available on the subject of natural products and drugs derived
therefrom in that it looks at the broad picture on how materials
and organisms from nature affect our health and how we have
combined our knowledge in chemistry, biology, and biodiversity to
promote our wellness from resources in the "molecular wilderness,"
with caveats on sustainable utilization of these resources. It is
therefore suitable, not only for readers interested in science and
medicine, but also for those with interest in policy issues
concerning sustainable development, environment, and issues
concerning interaction of science and society in general.
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